Potential role of plant extracts and phytochemicals against foodborne pathogens

F Ullah, M Ayaz, A Sadiq, F Ullah, I Hussain… - Applied Sciences, 2020 - mdpi.com
Foodborne diseases are one of the major causes of morbidity and mortality, especially in
low-income countries with poor sanitation and inadequate healthcare facilities. The foremost …

Recent advances in the discovery of novel antiprotozoal agents

SM Lee, MS Kim, F Hayat, D Shin - Molecules, 2019 - mdpi.com
Parasitic diseases have serious health, social, and economic impacts, especially in the
tropical regions of the world. Diseases caused by protozoan parasites are responsible for …

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri

B Bashyal, L Li, T Bains, A Debnath… - PLoS neglected …, 2017 - journals.plos.org
Protozoan parasites infect and kill millions of people worldwide every year, particularly in
developing countries where access to clean fresh water is limited. Among the most common …

Bis-pyrazolines: Synthesis, characterization and antiamoebic activity as inhibitors of growth of Entamoeba histolytica

AR Bhat, F Athar, A Azam - European journal of medicinal chemistry, 2009 - Elsevier
The cyclization of chalcone with N-4 substituted thiosemicarbazides under basic condition
led to the formation of new compounds, thiocarbamoyl bis-pyrazoline derivatives. The …

Synthesis, characterization and antiamoebic activity of some hydrazone and azole derivatives bearing pyridyl moiety as a promising heterocyclic scaffold

SM Siddiqui, A Salahuddin, A Azam - European Journal of Medicinal …, 2012 - Elsevier
In an effort to develop effective antiamoebic agents, some hydrazones and azoles
containing pyridyl moiety were synthesized and screened for in vitro antiamoebic activity …

Furanocoumarins from Ruta chalepensis with Amebicide Activity

AF Bazaldúa-Rodríguez, R Quintanilla-Licea… - Molecules, 2021 - mdpi.com
Entamoeba histolytica (protozoan; family Endomoebidae) is the cause of amoebiasis, a
disease related to high morbidity and mortality. Nowadays, this illness is considered a …

Synthesis and evaluation of 7-chloro-4-(piperazin-1-yl) quinoline-sulfonamide as hybrid antiprotozoal agents

A Salahuddin, A Inam, RL van Zyl, DC Heslop… - Bioorganic & medicinal …, 2013 - Elsevier
A new series of 4-aminochloroquinoline based sulfonamides were synthesized and
evaluated for antiamoebic and antimalarial activities. Out of the eleven compounds …

New derivatives of 3, 5-substituted-1, 4, 2-dioxazoles: synthesis and activity against Entamoeba histolytica

AR Bhat, F Athar, A Azam - European journal of medicinal chemistry, 2009 - Elsevier
Dioxazole derivatives (1–33) were synthesized in two steps via their corresponding oximes
(I–III). All the compounds were characterized using various spectroscopic techniques. A …

Parasitic diarrheal disease: drug development and targets

A Azam, MN Peerzada, K Ahmad - Frontiers in microbiology, 2015 - frontiersin.org
Diarrhea is the manifestation of gastrointestinal infection and is one of the major causes of
mortality and morbidity specifically among the children of less than 5 years age worldwide …

Metronidazole hydrazone conjugates: design, synthesis, antiamoebic and molecular docking studies

MF Ansari, SM Siddiqui, SM Agarwal… - Bioorganic & Medicinal …, 2015 - Elsevier
Abstract Metronidazole hydrazone conjugates (2–13) were synthesized and screened in
vitro for antiamoebic activity against HM1: IMSS strain of Entamoeba histolytica. Six …