Inflammation is a vital defense mechanism, creating hostile conditions for pathogens,
preventing the spread of tissue infection and repairing damaged tissues in humans and …

Objective One of the most critical reasons for limiting cancer treatment is the toxic effects of
anti-cancer drugs on healthy tissues and organs. This study aims to investigate the possible …

One of the biggest problems of cancer treatment is the harmful effects of these drugs on the
healthy tissues and organs of the organism. Our study aims to determine the possible …

Betulin and α-lipoic acid are naturally occurring substances with different biological
properties. Combining two phytochemical units into a conjugate is a frequently used method …

Silybum marianum (L.) Gaertn, commonly known as milk thistle, is an herbal medicine rich in
silymarin, a bioflavonoid complex. Historically, silymarin was used for treating liver diseases …

Silybin (SIB) is a hepatoprotective drug known for its poor oral bioavailability, attributed to its
classification as a class IV drug with significant metabolism during the first-pass effect. This …

Cardiovascular complications resulting from cisplatin (CS) are a significant factor that can
disrupt the treatment plan associated with this chemotherapy. This information led us to …

Background/Objectives: Breast cancer (BC) is a heterogeneous disease with multifactorial
origins, including environmental, genetic, and immunological factors. Inflammatory …

Background Exposure to ionizing radiation is inevitable due to its extensive use in industrial
and medical applications. The search for effective and safe natural therapeutic agents as …

It is well known that platinum-based antineoplastic agents, including cisplatin (CP), have
side effects that limit their use. Nefrotoxicity, neurotoxicity, and hemolytic anemia are the …