Chemistry in the bioactivity of chlorophylls: An overview
A Perez-Galvez, I Viera, M Roca - Current medicinal chemistry, 2017 - ingentaconnect.com
Background: In addition to the considerable number of different chlorophyll structures
originated naturally, prominent research is made to produce new specific semisynthetic …
originated naturally, prominent research is made to produce new specific semisynthetic …
Activity profiles of antimutagens: in vitro and in vivo data
MD Waters, HF Stack, MA Jackson… - Mutation Research …, 1996 - Elsevier
In this review, retinol, chlorophyllin, and N-acetylcysteine are examined and compared with
regard to their antimutagenic activity against some promutagens and a group of direct-acting …
regard to their antimutagenic activity against some promutagens and a group of direct-acting …
Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo [a] pyrene: studies of enzyme inhibition, molecular complex formation and degradation …
N Tachino, D Guo, WM Dashwood, S Yamane… - Mutation Research …, 1994 - Elsevier
Mechanisms of the antimutagenic action of chlorophyllin (CHL) towards benzo [a] pyrene
(BP) were studied in vitro. In the Salmonella assay, CHL inhibited the mutagenic activity of …
(BP) were studied in vitro. In the Salmonella assay, CHL inhibited the mutagenic activity of …
Binding of polycyclic planar mutagens to chlorophyllin resulting in inhibition of the mutagenic activity
S Arimoto, S Fukuoka, C Itome, H Nakano, H Rai… - Mutation Research …, 1993 - Elsevier
Chlorophyllin is known to inhibit the mutagenicity of a variety of compounds. Using highly
purified samples of chlorophyllin and its family compounds, we studied the mechanism of …
purified samples of chlorophyllin and its family compounds, we studied the mechanism of …
Antioxidant activity and antiproliferative action of methanol extracts of 4 different colored bell peppers (Capsicum annuum l.)
Methanol extracts of 4 different colored (red, orange, yellow, and green) bell peppers
(Capsicum annuum L.) were examined to (1) determine the total phenolic content (TPC),(2) …
(Capsicum annuum L.) were examined to (1) determine the total phenolic content (TPC),(2) …
Functional Interaction Between BRCA1 and DNA Repair in Yeast May Uncover a Role of RAD50, RAD51, MRE11A, and MSH6 Somatic Variants in Cancer …
L Maresca, S Lodovichi, A Lorenzoni, T Cervelli… - Frontiers in …, 2018 - frontiersin.org
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB)
and mismatch repair (MMR) may contribute to breast and ovarian cancer development …
and mismatch repair (MMR) may contribute to breast and ovarian cancer development …
Antimutagenic potency of chlorophyllin in the Salmonella assay and its correlation with binding constants of mutagen‐inhibitor complexes
R Dashwood, D Guo - Environmental and molecular …, 1993 - Wiley Online Library
Chlorophyllin (CHL) is a water‐soluble salt of chlorophyll that exhibits antimutagenic activity
in short‐term genotoxicity assays and inhibits carcinogen‐DNA binding in vivo. The …
in short‐term genotoxicity assays and inhibits carcinogen‐DNA binding in vivo. The …
Porphyrins as potential inhibitors against exposure to carcinogens and mutagens
H Hayatsu, T Negishi, S Arimoto, T Hayatsu - … Research/Fundamental and …, 1993 - Elsevier
Studies have shown that there are many substances that can interfere with the actions of
carcinogens and mutagens. Porphyrins, which often are constituents of diet, are a class of …
carcinogens and mutagens. Porphyrins, which often are constituents of diet, are a class of …
Investigation of genotoxic and antigenotoxic activities of chlorophylls and chlorophyllin in cultured V79 cells
GC Bez, BQ Jordão, VEP Vicentini… - … /Genetic Toxicology and …, 2001 - Elsevier
Chlorophyll and its derivatives are examples of plant compounds (purified and/or extracted)
which appear to protect DNA from damage caused by chemical or physical agents, although …
which appear to protect DNA from damage caused by chemical or physical agents, although …
Identification of natural antimutagens with modulating effects on DNA repair
B Vuković-Gačić, D Simić - Antimutagenesis and Anticarcinogenesis …, 1993 - Springer
The results of a study of bioantimutagenesis, with emphasis on natural antimutagens from
plant extracts with modulating effects on DNA repair in Escherichia coli bacteria are …
plant extracts with modulating effects on DNA repair in Escherichia coli bacteria are …