Organochlorine pesticides: Agrochemicals with potent endocrine-disrupting properties in fish

CJ Martyniuk, AC Mehinto, ND Denslow - Molecular and cellular …, 2020 - Elsevier
Organochlorine pesticides (OCPs) are persistent environmental contaminants that act as
endocrine disruptors and organ system toxicants. These pesticides (eg …

Endocrine disruptors of inhibiting testicular 3β-hydroxysteroid dehydrogenase

S Zhang, J Mo, Y Wang, C Ni, X Li, Q Zhu… - Chemico-Biological …, 2019 - Elsevier
Testicular 3β-hydroxysteroid dehydrogenase (HSD3B) is a steroidogenic enzyme,
catalyzing the conversion of 3β-hydroxysteroids into 3-keto-steroids. Two distinct isoforms in …

Pesticide methoxychlor promotes the epigenetic transgenerational inheritance of adult-onset disease through the female germline

M Manikkam, MM Haque, C Guerrero-Bosagna… - PloS one, 2014 - journals.plos.org
Environmental compounds including fungicides, plastics, pesticides, dioxin and
hydrocarbons can promote the epigenetic transgenerational inheritance of adult-onset …

Association between organochlorine pesticide levels in breast milk and their effects on female reproduction in a Taiwanese population

MW Chen, HM Santos, DE Que, YY Gou… - International Journal of …, 2018 - mdpi.com
Only few studies have focused on organochlorine pesticides (OCPs) in breast milk and the
related health risks for women in Taiwan. Our goal is to examine breast milk OCPs and their …

Characterization of endocrine-disrupting chemicals based on hormonal balance disruption in male and female adult rats

N Quignot, M Arnaud, F Robidel, A Lecomte… - Reproductive …, 2012 - Elsevier
Reproductive functions are controlled by a finely tuned balance between estrogens and
androgens. To further characterize the gonadal pathways leading to hormonal balance …

Methoxychlor induces apoptosis via mitochondria-and FasL-mediated pathways in adult rat testis

S Vaithinathan, B Saradha, PP Mathur - Chemico-biological interactions, 2010 - Elsevier
In the past few years, there has been much concern about the adverse health effects of
environmental contaminants in general and organochlorine in particular. Studies have …

In vivo effects of Aspalathus linearis (rooibos) on male rat reproductive functions

CS Opuwari, TK Monsees - Andrologia, 2014 - Wiley Online Library
Aspalathus linearis (rooibos tea) may improve sperm function owing to its antioxidant
properties. To test this hypothesis, male rats were given 2% or 5% rooibos tea for 52 days …

Suppression of fertility in male albino rats following the administration of 50% ethanolic extract of Aegle marmelos

A Chauhan, M Agarwal, S Kushwaha, A Mutreja - Contraception, 2007 - Elsevier
BACKGROUND: Plants have served as a natural source of antifertility substances. The
reactivated interest in the evaluation of some lead plants for fertility prompted us to …

Methoxychlor reduces estradiol levels by altering steroidogenesis and metabolism in mouse antral follicles in vitro

MS Basavarajappa, ZR Craig… - Toxicology and applied …, 2011 - Elsevier
The organochlorine pesticide methoxychlor (MXC) is a known endocrine disruptor that
affects adult rodent females by causing reduced fertility, persistent estrus, and ovarian …

Effects of anabolic androgenic steroids on the development and expression of running wheel activity and circadian rhythms in male rats

MY McGinnis, AR Lumia, MJ Tetel… - Physiology & …, 2007 - Elsevier
In humans, anabolic androgenic steroid (AAS) use has been associated with hyperactivity
and disruption of circadian rhythmicity. We used an animal model to determine the impact of …