A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes

J Riyaphan, DC Pham, MK Leong, CF Weng - Biomolecules, 2021 - mdpi.com
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors,
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …

Antioxidant activity of polyphenolic plant extracts

D Stagos - Antioxidants, 2019 - mdpi.com
Plant polyphenols are secondary metabolites characterized by one or more hydroxyl groups
binding to one or more aromatic rings [1]. Several thousand polyphenolic molecules have …

Green Synthesis of Gold Nanoparticles Capped with Procyanidins from Leucosidea sericea as Potential Antidiabetic and Antioxidant Agents

UM Badeggi, E Ismail, AO Adeloye, S Botha… - Biomolecules, 2020 - mdpi.com
In this study, procyanidins fractions of dimers and trimers (F1–F2) from the Leucosidea
sericea total extract (LSTE) were investigated for their chemical constituents. The total …

New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects

H Kashtoh, KH Baek - Plants, 2023 - mdpi.com
The rising predominance of type 2 diabetes, combined with the poor medical effects seen
with commercially available anti-diabetic medications, has motivated the development of …

Nutritional and medicinal plants as potential sources of enzyme inhibitors toward the bioactive functional foods: an updated review

H Saleem, A Yaqub, R Rafique… - Critical Reviews in …, 2024 - Taylor & Francis
Enzymes are biologically active complex protein molecules that catalyze most chemical
reactions in living organisms, and their inhibitors accelerate biological processes. This …

[HTML][HTML] Anti-oxidant potential of plants and probiotic spp. in alleviating oxidative stress induced by H2O2

H Kumar, R Dhalaria, S Guleria, R Cimler… - Biomedicine & …, 2023 - Elsevier
Cells produce reactive oxygen species (ROS) as a metabolic by-product. ROS molecules
trigger oxidative stress as a feedback response that significantly initiates biological …

Alpha-Glucosidase and Alpha-Amylase Inhibitory Activities, Molecular Docking, and Antioxidant Capacities of Salvia aurita Constituents

NGER Etsassala, JA Badmus, JL Marnewick, EI Iwuoha… - Antioxidants, 2020 - mdpi.com
Diabetes mellitus (DM) is one of the most dangerous metabolic diseases with a high rate of
mortality worldwide. It is well known that insulin resistance and deficiency in insulin …

A Comparative Analysis of Radical Scavenging, Antifungal and Enzyme Inhibition Activity of 3′-8 ″-Biflavones and Their Monomeric Subunits

I Jurčević Šangut, B Šarkanj, E Karalija, D Šamec - Antioxidants, 2023 - mdpi.com
Biflavonoids are dimeric forms of flavonoids that have recently gained importance as an
effective new scaffold for drug discovery. In particular, 3′-8 ″-biflavones exhibit antiviral …

[HTML][HTML] Antidiabetic compounds from medicinal plants traditionally used for the treatment of diabetes in Africa: A review update (2015–2020)

A Mohammed, N Tajuddeen - South african journal of botany, 2022 - Elsevier
Africa has a rich biodiversity of plants and an active traditional medicine system that takes
advantage of the rich biodiversity to treat various diseases, including diabetes mellitus (DM) …