Endocrine disrupting chemicals: exposure, effects on human health, mechanism of action, models for testing and strategies for prevention

B Yilmaz, H Terekeci, S Sandal… - Reviews in endocrine and …, 2020 - Springer
Abstract Endocrine Disrupting Chemicals (EDCs) are a global problem for environmental
and human health. They are defined as “an exogenous chemical, or mixture of chemicals …

Prevalence of exposure of heavy metals and their impact on health consequences

K Rehman, F Fatima, I Waheed… - Journal of cellular …, 2018 - Wiley Online Library
Even in the current era of growing technology, the concentration of heavy metals present in
drinking water is still not within the recommended limits as set by the regulatory authorities in …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

The role of cadmium in obesity and diabetes

AA Tinkov, T Filippini, OP Ajsuvakova, J Aaseth… - Science of the Total …, 2017 - Elsevier
Multiple studies have shown an association between environmental exposure to hazardous
chemicals including toxic metals and obesity, diabetes, and metabolic syndrome. At the …

[HTML][HTML] Occurrence, formation, environmental fate and risks of environmentally persistent free radicals in biochars

ES Odinga, MG Waigi, FO Gudda, J Wang… - Environment …, 2020 - Elsevier
Biochars are used globally in agricultural crop production and environmental remediation.
However, environmentally persistent free radicals (EPFRs), which are stable emerging …

Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes

F Yang, R Pei, Z Zhang, J Liao, W Yu, N Qiao, Q Han… - Toxicology in Vitro, 2019 - Elsevier
The aim of this study was to investigate the effects of excessive copper (Cu)-induced
cytotoxicity on oxidative stress and mitochondrial apoptosis in chicken hepatocytes. Chicken …

[HTML][HTML] Cadmium exposure impairs pancreatic β-cell function and exaggerates diabetes by disrupting lipid metabolism

H Hong, Y Xu, J Xu, J Zhang, Y Xi, H Pi, L Yang… - Environment …, 2021 - Elsevier
Cadmium is known as an environmental pollutant that contributes to pancreatic damage and
the pathogenesis of diabetes. However, less attention has been devoted to elucidating the …

Mitochondrial dysfunction in schizophrenia: pathways, mechanisms and implications

A Rajasekaran, G Venkatasubramanian, M Berk… - Neuroscience & …, 2015 - Elsevier
Mitochondria play a critical role in regulating cellular functions including bioenergetics,
calcium homeostasis, redox signalling, and apoptotic cell death. Mitochondria are also …

Selenium and zinc protections against metal-(loids)-induced toxicity and disease manifestations: a review

MM Rahman, KFB Hossain, S Banik, MT Sikder… - Ecotoxicology and …, 2019 - Elsevier
Metals are ubiquitous in the environment due to huge industrial applications in the form of
different chemicals and from extensive mining activities. The frequent exposures to metals …

[HTML][HTML] Environmental cadmium exposure and pancreatic cancer: Evidence from case control, animal and in vitro studies

VR Djordjevic, DR Wallace, A Schweitzer… - Environment …, 2019 - Elsevier
Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scarce. Some
of established risk factors of PC are connected to an increased cadmium (Cd) body burden …