[HTML][HTML] Risk stratification and medical therapy of pulmonary arterial hypertension

N Galiè, RN Channick, RP Frantz… - European …, 2019 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) remains a severe clinical condition despite the
availability over the past 15 years of multiple drugs interfering with the endothelin, nitric …

Phase 3 trial of sotatercept for treatment of pulmonary arterial hypertension

MM Hoeper, DB Badesch, HA Ghofrani… - … England Journal of …, 2023 - Mass Medical Soc
Background Pulmonary arterial hypertension is a progressive disease involving proliferative
remodeling of the pulmonary vessels. Despite therapeutic advances, the disease-associated …

[HTML][HTML] 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

M Humbert, G Kovacs, MM Hoeper… - European …, 2022 - publications.ersnet.org
2022 ESC/ERS pulmonary hypertension guidelines incorporate changes and adaptations
focusing on clinical management https://bit. ly/3QtUvb4

Sotatercept for the treatment of pulmonary arterial hypertension

M Humbert, V McLaughlin, JSR Gibbs… - … England Journal of …, 2021 - Mass Medical Soc
Background Pulmonary arterial hypertension is characterized by pulmonary vascular
remodeling, cellular proliferation, and poor long-term outcomes. Dysfunctional bone …

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary …

M Humbert, G Kovacs, MM Hoeper… - European heart …, 2022 - academic.oup.com
Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair

K Sun, Y Li, J Jin - Signal transduction and targeted therapy, 2021 - nature.com
The response of immune cells in cardiac injury is divided into three continuous phases:
inflammation, proliferation and maturation. The kinetics of the inflammatory and proliferation …

2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease …

G Hansmann, M Koestenberger, TP Alastalo… - The Journal of Heart and …, 2019 - Elsevier
The European Pediatric Pulmonary Vascular Disease Network is a registered, non-profit
organization that strives to define and develop effective, innovative diagnostic methods and …

Three-versus two-drug therapy for patients with newly diagnosed pulmonary arterial hypertension

KM Chin, O Sitbon, M Doelberg, J Feldman… - Journal of the American …, 2021 - jacc.org
Background In pulmonary arterial hypertension (PAH), there are no data comparing initial
triple oral therapy with initial double oral therapy. Objectives TRITON (The Efficacy and …

Hypoxia-inducible factor signaling in pulmonary hypertension

SS Pullamsetti, A Mamazhakypov… - The Journal of …, 2020 - Am Soc Clin Investig
Pulmonary hypertension (PH) is characterized by pulmonary artery remodeling that can
subsequently culminate in right heart failure and premature death. Emerging evidence …

Novel insights on the pulmonary vascular consequences of COVID-19

F Potus, V Mai, M Lebret, S Malenfant… - … of Physiology-Lung …, 2020 - journals.physiology.org
In the last few months, the number of cases of a new coronavirus-related disease (COVID-
19) rose exponentially, reaching the status of a pandemic. Interestingly, early imaging …