Recent advances in single-molecule tracking and imaging techniques
Since the early 1990s, single-molecule detection in solution at room temperature has
enabled direct observation of single biomolecules at work in real time and under …
enabled direct observation of single biomolecules at work in real time and under …
Mechanical regulation of nucleocytoplasmic translocation in mesenchymal stem cells: characterization and methods for investigation
L Boeri, D Albani, MT Raimondi, E Jacchetti - Biophysical reviews, 2019 - Springer
Mesenchymal stem cells (MSCs) have immune-modulatory and tissue-regenerative
properties that make them a suitable and promising tool for cell-based therapy application …
properties that make them a suitable and promising tool for cell-based therapy application …
[HTML][HTML] 3D photopolymerized microstructured scaffolds influence nuclear deformation, nucleo/cytoskeletal protein organization, and gene regulation in mesenchymal …
F Donnaloja, MT Raimondi, L Messa… - APL …, 2023 - pubs.aip.org
Mechanical stimuli from the extracellular environment affect cell morphology and
functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown in a custom …
functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown in a custom …
128-channel high-linearity resolution-adjustable time-to-digital converters for LiDAR applications: Software predictions and hardware implementations
This article proposes a new calibration method, called the mixed-binning (MB) method, to
pursue high-linearity time-to-digital converters (TDCs) for light detection and ranging …
pursue high-linearity time-to-digital converters (TDCs) for light detection and ranging …
Stochastic or not? method to predict and quantify the stochastic effects on the association reaction equilibria in nanoscopic systems
The stochastic nature of chemical reaction and impact of the stochasticity on their evolution
is soundly documented. Both theoretical predictions and emerging experimental evidence …
is soundly documented. Both theoretical predictions and emerging experimental evidence …
Revealing atomic-scale molecular diffusion of a plant-transcription factor WRKY domain protein along DNA
Transcription factor (TF) target search on genome is highly essential for gene expression
and regulation. High-resolution determination of TF diffusion along DNA remains technically …
and regulation. High-resolution determination of TF diffusion along DNA remains technically …
Segmentation of 3D trajectories acquired by TSUNAMI microscope: an application to EGFR trafficking
Whereas important discoveries made by single-particle tracking have changed our view of
the plasma membrane organization and motor protein dynamics in the past three decades …
the plasma membrane organization and motor protein dynamics in the past three decades …
Maximum likelihood detection on images
We consider the problem of point target detection on images and focal plane arrays (FPA).
Imaging sensors are becoming ubiquitous tools in several applications, such as biomedical …
Imaging sensors are becoming ubiquitous tools in several applications, such as biomedical …
Measuring DNA hybridization kinetics in live cells using a time-resolved 3D single-molecule tracking method
Single-molecule detection enables direct characterization of annealing/melting kinetics of
nucleic acids without the need for synchronization of molecular states, but the current …
nucleic acids without the need for synchronization of molecular states, but the current …
3D single-molecule tracking enables direct hybridization kinetics measurement in solution
Single-molecule measurements of DNA hybridization kinetics are mostly performed on a
surface or inside a trap. Here we demonstrate a time-resolved, 3D single-molecule tracking …
surface or inside a trap. Here we demonstrate a time-resolved, 3D single-molecule tracking …