Alopecia areata: an update on etiopathogenesis, diagnosis, and management

C Zhou, X Li, C Wang, J Zhang - Clinical Reviews in Allergy & …, 2021 - Springer
Alopecia areata (AA) is a common chronic tissue-specific autoimmune disease, resulting in
hair loss, that affects up to 2% of the general population. The exact pathobiology of AA has …

Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options

A Sterkens, J Lambert, A Bervoets - Clinical and experimental medicine, 2021 - Springer
Patients suffering from alopecia areata (AA) can lose hair in focal regions, the complete
scalp, including eyelashes and eyebrows, or even the entire body. The exact pathology is …

Two phase 3 trials of baricitinib for alopecia areata

B King, M Ohyama, O Kwon, A Zlotogorski… - … England Journal of …, 2022 - Mass Medical Soc
Background Alopecia areata is an autoimmune condition characterized by rapid hair loss in
the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral …

[HTML][HTML] Efficacy and safety of the oral Janus kinase inhibitor baricitinib in the treatment of adults with alopecia areata: phase 2 results from a randomized controlled …

B King, J Ko, S Forman, M Ohyama… - Journal of the American …, 2021 - Elsevier
Background There are no treatments approved by the Food and Drug Administration for
alopecia areata. Objective To evaluate the efficacy and safety of baricitinib in patients with≥ …

Alopecia areata: Current understanding of the pathophysiology and update on therapeutic approaches, featuring the Japanese Dermatological Association guidelines

M Fukuyama, T Ito, M Ohyama - The Journal of dermatology, 2022 - Wiley Online Library
Alopecia areata (AA) is a relatively common nonscarring hairloss disease characterized by
an autoimmune response to anagen hair follicles (HFs). Accumulated evidence suggests …

Alopecia areata: current treatments and new directions

D Dahabreh, S Jung, Y Renert-Yuval, J Bar… - American Journal of …, 2023 - Springer
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …

“'You lose your hair, what's the big deal?' I was so embarrassed, I was so self-conscious, I was so depressed:” a qualitative interview study to understand the …

NVJ Aldhouse, H Kitchen, S Knight, J Macey… - Journal of Patient …, 2020 - Springer
Background Alopecia areata (AA) is characterized by hair loss that can affect the scalp and
body. This study describes the psychosocial burden of AA. Methods Participants diagnosed …

The Alopecia Areata Investigator Global Assessment scale: a measure for evaluating clinically meaningful success in clinical trials

KW Wyrwich, H Kitchen, S Knight… - British Journal of …, 2020 - academic.oup.com
Background Content‐valid and clinically meaningful instruments are required to evaluate
outcomes of therapeutic interventions in alopecia areata (AA). Objectives To develop an …

Development of clinician-reported outcome (ClinRO) and patient-reported outcome (PRO) measures for eyebrow, eyelash and nail assessment in alopecia areata

KW Wyrwich, H Kitchen, S Knight… - American journal of …, 2020 - Springer
Background Eyebrow and eyelash hair loss and nail damage—in addition to scalp hair loss—
are important signs/symptoms of alopecia areata (AA) to patients and deserve assessment …

Patient characteristics and disease burden of alopecia areata in the Danish Skin Cohort

YMF Andersen, L Nymand, AM DeLozier, R Burge… - BMJ open, 2022 - bmjopen.bmj.com
Purpose Alopecia areata (AA) is a common disorder of patchy hair loss which carries a
substantial psychological burden for patients. The current understanding of AA prevalence …