Fish lymphocytes: an evolutionary equivalent of mammalian innate-like lymphocytes?
Lymphocytes are the responsible of adaptive responses, as they are classically described,
but evidence shows that subpopulations of mammalian lymphocytes may behave as innate …
but evidence shows that subpopulations of mammalian lymphocytes may behave as innate …
Cluster of differentiation antigens: essential roles in the identification of teleost fish T lymphocytes
H Tian, J Xing, X Tang, H Chi, X Sheng… - Marine Life Science & …, 2022 - Springer
Cluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes
and other cells associated with the immune system. Antibodies that react with CD antigens …
and other cells associated with the immune system. Antibodies that react with CD antigens …
CD4: a vital player in the teleost fish immune system
CD4 is a nonpolymorphic transmembrane glycoprotein molecule that is expressed on the
surface of T-helper cells and plays an essential role in the immune response. It functions as …
surface of T-helper cells and plays an essential role in the immune response. It functions as …
Overview of fish immunity
R Castro, C Tafalla - Mucosal health in aquaculture, 2015 - Elsevier
The purpose of this chapter is to provide readers with a general overview of the fish immune
system, including commonalities and particularities in comparison with higher vertebrate …
system, including commonalities and particularities in comparison with higher vertebrate …
T cell diversity and TcR repertoires in teleost fish
R Castro, D Bernard, MP Lefranc, A Six… - Fish & shellfish …, 2011 - Elsevier
In vertebrates, the diverse and extended range of antigenic motifs is matched to large
populations of lymphocytes. The concept of immune repertoire was proposed to describe …
populations of lymphocytes. The concept of immune repertoire was proposed to describe …
Fish T cells: recent advances through genomics
This brief review is intended to provide a concise overview of the current literature
concerning T cells, advances in identifying distinct T cell functional subsets, and in …
concerning T cells, advances in identifying distinct T cell functional subsets, and in …
Isolation and characterization of salmonid CD4+ T cells
K Maisey, R Montero, Y Corripio-Miyar… - The Journal of …, 2016 - journals.aai.org
This study reports the isolation and functional characterization of rainbow trout
(Oncorhynchus mykiss) CD4-1+ T cells and the establishment of an IL-15–dependent CD4 …
(Oncorhynchus mykiss) CD4-1+ T cells and the establishment of an IL-15–dependent CD4 …
First Demonstration of Antigen Induced Cytokine Expression by CD4-1+ Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)
Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release
cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic …
cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic …
IL-2–mTORC1 signaling coordinates the STAT1/T-bet axis to ensure Th1 cell differentiation and anti-bacterial immune response in fish
K Ai, K Li, X Jiao, Y Zhang, J Li, Q Zhang, X Wei… - PLoS …, 2022 - journals.plos.org
Utilization of specialized Th1 cells to resist intracellular pathogenic infection represents an
important innovation of adaptive immunity. Although transcriptional evidence indicates the …
important innovation of adaptive immunity. Although transcriptional evidence indicates the …
Identification of Treg-like cells in Tetraodon: insight into the origin of regulatory T subsets during early vertebrate evolution
Y Wen, W Fang, LX Xiang, RL Pan, JZ Shao - Cellular and Molecular Life …, 2011 - Springer
Abstract CD4+ CD25+ Foxp3+ regulatory T cells (Treg cells) are critical for the maintenance
of peripheral tolerance, and the suppression of autoimmune diseases and even tumors …
of peripheral tolerance, and the suppression of autoimmune diseases and even tumors …