Translation and functional roles of circular RNAs in human cancer

M Lei, G Zheng, Q Ning, J Zheng, D Dong - Molecular cancer, 2020 - Springer
Circular RNAs (circRNAs) are a new class of non-coding RNAs formed by covalently closed
loops through backsplicing. Recent methodologies have enabled in-depth characterization …

[HTML][HTML] Advances in circular RNA and its applications

X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …

Circular RNA translation, a path to hidden proteome

T Sinha, C Panigrahi, D Das… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Functional proteins in the cell are translated from the messenger RNA (mRNA) molecules,
constituting less than 5% of the cellular transcriptome. The majority of the RNA molecules in …

The new function of circRNA: translation

Y Shi, X Jia, J Xu - Clinical and Translational Oncology, 2020 - Springer
Circular RNAs (circRNAs) have been considered a special class of non-coding RNAs
without 5′ caps and 3′ tails which are covalently closed RNA molecules generated by …

Translation of noncoding RNAs and cancer

B Zhou, H Yang, C Yang, Y Bao, S Yang, J Liu, Y Xiao - Cancer letters, 2021 - Elsevier
The human genome contains thousands of noncoding RNAs (ncRNAs), which are thought to
lack open reading frames (ORFs) and cannot be translated. Some ncRNAs reportedly have …

Translation role of circRNAs in cancers

Y Lu, Z Li, C Lin, J Zhang, Z Shen - Journal of Clinical …, 2021 - Wiley Online Library
Circular RNAs (circRNAs) constitute a class of covalently closed RNA molecules. With the
continuous advancement of high‐throughput sequencing technology and bioinformatics …

CircRNA and lncRNA-encoded peptide in diseases, an update review

Q Yi, J Feng, W Lan, H Shi, W Sun, W Sun - Molecular Cancer, 2024 - Springer
Abstract Non-coding RNAs (ncRNAs), including circular RNAs (circRNAs) and long non-
coding RNAs (lncRNAs), are unique RNA molecules widely identified in the eukaryotic …

The important regulatory roles of circRNA-encoded proteins or peptides in cancer pathogenesis

L Zhang, H Gao, X Li, F Yu, P Li - … Journal of Oncology, 2023 - spandidos-publications.com
Circular RNAs (circRNAs) represent a class of RNA molecules characterized by their
covalently closed structures. There are three types of circRNAs, namely exonic circRNAs …

circRNAs signature as potential diagnostic and prognostic biomarker for diabetes mellitus and related cardiovascular complications

M Zaiou - Cells, 2020 - mdpi.com
Circular RNAs (circRNAs) belong to the ever-growing class of naturally occurring noncoding
RNAs (ncRNAs) molecules. Unlike linear RNA, circRNAs are covalently closed transcripts …

Identification, biogenesis, function, and mechanism of action of circular RNAs in plants

R Liu, Y Ma, T Guo, G Li - Plant communications, 2023 - cell.com
Circular RNAs (circRNAs) are a class of single-stranded, closed RNA molecules with unique
functions that are ubiquitously expressed in all eukaryotes. The biogenesis of circRNAs is …