Chronic kidney disease (CKD) refers to a range of various pathophysiological processes
correlated with abnormal renal function and a progressive loss in GFR. Just as dysbiosis …

Background: The kynurenine pathway (KP) is the major catabolic pathway for tryptophan
degradation. The KP plays an important role as the sole de novo nicotinamide adenine …

Tryptophan metabolism through the kynurenine pathway influences molecular processes
critical to healthy aging including immune signaling, redox homeostasis, and energy …

Tryptophan (TRP) is an essential dietary amino acid that, unless otherwise committed to
protein synthesis, undergoes metabolism via the Tryptophan-Kynurenine (TRP-KYN) …

Background Diabetic kidney disease (DKD) is among the most important causes for chronic
kidney disease. Anthocyanins (ANT) are polyphenolic compounds present in various food …

Kidney diseases have become one of the most common health care problems. Due to a
growing number of advanced aged patients with concomitant disorders the prevalence of …

Background and Aims Acute kidney injury (AKI) has a poor prognosis in cirrhosis. Given the
variability of creatinine, the prediction of AKI and dialysis by other markers is needed. The …

Chronic kidney disease (CKD) is a serious public health problem characterized by
progressive kidney function loss leading to end-stage renal disease (ESRD) that demands …

Chronic kidney disease (CKD) occurrence is rising all over the world. Its presence is
associated with an increased risk of premature death from cardiovascular disease (CVD) …

Kynurenic acid (KYNA) is an antioxidant degradation product of tryptophan that has been
shown to have a variety of cytoprotective, neuroprotective and neuronal signalling …