[HTML][HTML] A deep-learning strategy to identify cell types across species from high-density extracellular recordings
M Beau, DJ Herzfeld, F Naveros, ME Hemelt… - bioRxiv, 2024 - ncbi.nlm.nih.gov
High-density probes allow electrophysiological recordings from many neurons
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …
simultaneously across entire brain circuits but don't reveal cell type. Here, we develop a …
Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells
Molecular layer interneurons (MLIs) account for approximately 80% of the inhibitory
interneurons in the cerebellar cortex and are vital to cerebellar processing. MLIs are thought …
interneurons in the cerebellar cortex and are vital to cerebellar processing. MLIs are thought …
[HTML][HTML] Cerebellar circuits for disinhibition and synchronous inhibition
The cerebellar cortex contributes to diverse behaviors by transforming mossy fiber inputs
into predictions in the form of Purkinje cell (PC) outputs, and then refining those predictions …
into predictions in the form of Purkinje cell (PC) outputs, and then refining those predictions …
Implications of variable synaptic weights for rate and temporal coding of cerebellar outputs
Purkinje cell (PC) synapses onto cerebellar nuclei (CbN) neurons allow signals from the
cerebellar cortex to influence the rest of the brain. PCs are inhibitory neurons that …
cerebellar cortex to influence the rest of the brain. PCs are inhibitory neurons that …
Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)
Cerebellar dysfunction leads to postural instability. Recent work in freely moving rodents has
transformed investigations of cerebellar contributions to posture. However, the combined …
transformed investigations of cerebellar contributions to posture. However, the combined …
Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate …
Unipolar brush cells (UBCs) are excitatory interneurons in the cerebellar cortex that receive
mossy fiber (MF) inputs and excite granule cells. The UBC population responds to brief burst …
mossy fiber (MF) inputs and excite granule cells. The UBC population responds to brief burst …
The Effect of Nucleo-Olivary Stimulation on Climbing Fiber EPSPs in Purkinje Cells
J Öhman, E Sjölin, M Cundari, F Johansson, M Gilbert… - The Cerebellum, 2024 - Springer
Climbing fibers, connecting the inferior olive and Purkinje cells, form the nervous system's
strongest neural connection. These fibers activate after critical events like motor errors or …
strongest neural connection. These fibers activate after critical events like motor errors or …
Beta-band oscillations and spike-local field potential synchronization in the motor cortex are correlated with movement deficits in an exercise-induced fatigue mouse …
X Zhao, H Wang, K Li, S Chen, L Hou - Cognitive Neurodynamics, 2025 - Springer
Fatigue, a complex and multifaceted symptom, profoundly influences quality of life,
particularly among individuals suffering from chronic medical conditions or neurological …
particularly among individuals suffering from chronic medical conditions or neurological …
The olivary input to the cerebellum dissociates sensory events from movement plans
Neurons in the inferior olive are thought to anatomically organize the Purkinje cells (P-cells)
of the cerebellum into computational modules, but what is computed by each module? Here …
of the cerebellum into computational modules, but what is computed by each module? Here …
Mesoscale Ca2+ imaging reveals networks of Purkinje cell dendritic and somatic modulation, with divergent roles of activity versus correlation during behavior
ML Streng, RE Carter, BW Kottke, K Togneri… - bioRxiv, 2023 - biorxiv.org
A major challenge in cerebellar physiology is determining how the stereotypic, conserved
circuitry of the cerebellar cortex, with its dominant parasagittal and transverse architectures …
circuitry of the cerebellar cortex, with its dominant parasagittal and transverse architectures …