Skeletal muscle cells opto-stimulation by intramembrane molecular transducers

I Venturino, V Vurro, S Bonfadini, M Moschetta… - Communications …, 2023 - nature.com
Optical stimulation and control of muscle cell contraction opens up a number of interesting
applications in hybrid robotic and medicine. Here we show that recently designed molecular …

Optical modulation of excitation-contraction coupling in human-induced pluripotent stem cell-derived cardiomyocytes

V Vurro, B Federici, C Ronchi, C Florindi, V Sesti… - IScience, 2023 - cell.com
Non-genetic photostimulation is a novel and rapidly growing multidisciplinary field that aims
to induce light-sensitivity in living systems by exploiting exogeneous phototransducers …

Design Parameters and Human Biocompatibility Assessment Protocols for Organic Semiconducting Neural Interfaces: Toward a Printed Artificial Retina with Color …

CP Sherwood, R Crovador, JA Posar… - Advanced Materials …, 2023 - Wiley Online Library
Organic semiconductors have emerged as promising neural interfacing materials due to
their innate biocompatibility, soft mechanical properties, and mixed electron/ion conduction …

[HTML][HTML] Light-triggered cardiac microphysiological model

V Vurro, K Shani, HAM Ardoña, JF Zimmerman… - APL …, 2023 - pubs.aip.org
Light is recognized as an accurate and noninvasive tool for stimulating excitable cells. Here,
we report on a non-genetic approach based on organic molecular phototransducers that …

A perspective on the use of light as a driving element for bio-hybrid actuation

V Vurro, I Venturino, G Lanzani - Applied Physics Letters, 2022 - pubs.aip.org
Bio-hybrid actuators are devices based on muscle cells or tissues, designed to exploit the
force generated by the biological element to execute an action or a movement. Typically …

Shedding light on thermally induced optocapacitance at the organic biointerface

G Bondelli, S Sardar, G Chiaravalli… - The Journal of …, 2021 - ACS Publications
Photothermal perturbation of the cell membrane is typically achieved using transducers that
convert light into thermal energy, eventually heating the cell membrane. In turn, this leads to …

Optical excitation of organic semiconductors as a highly selective strategy to induce vascular regeneration and tissue repair

F Moccia, S Negri, P Faris, C Ronchi, F Lodola - Vascular Pharmacology, 2022 - Elsevier
Therapeutic neovascularization represents a promising strategy to rescue the vascular
network and restore organ function in cardiovascular disorders (CVDs), including acute …

Resonant Enhancement of Polymer–Cell Optostimulation by a Plasmonic Metasurface

A Maity, S Perotto, M Moschetta, H Hua, S Sardar… - ACS …, 2022 - ACS Publications
Organic semiconductors have shown great potential as efficient bioelectronic materials.
Specifically, photovoltaic polymers such as the workhorse poly (thiophene) derivatives …

A Polymer Bio–Photoelectrolytic Platform for Electrical Signal Measurement and for Light Modulation of Ion Fluxes and Proliferation in a Neuroblastoma Cell Line

M Ciocca, S Marcozzi, P Mariani… - Advanced …, 2023 - Wiley Online Library
Light control of living systems is an emerging field in bioelectronics, in regenerative
medicine and cell‐based therapy. Herein, the design of a semitransparent bio …

Propagation and localization of light in one-dimensional nonlinear photonic crystals embedded polyvinylidene fluoride/graphene oxide layers

Y Liu, WG Liu, YC Zhu, S Zhou, ZH Dai, X Sun, SB Ge… - Optical Materials, 2024 - Elsevier
Propagation and localization of light in one-dimensional nonlinear photonic crystals (1D-
NPhCs) are analyzed in this paper, which consist of alternating layers with varying dielectric …