Migraine and risk of stroke

LR Øie, T Kurth, S Gulati, DW Dodick - Journal of Neurology …, 2020 - jnnp.bmj.com
Migraine and stroke are two common and heterogeneous neurovascular disorders
responsible for a significant burden for those affected and a great economic cost for the …

Discovery of shared genomic loci using the conditional false discovery rate approach

OB Smeland, O Frei, A Shadrin, K O'Connell, CC Fan… - Human genetics, 2020 - Springer
In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

G Bjornsdottir, MA Chalmer, L Stefansdottir… - Nature Genetics, 2023 - nature.com
Migraine is a complex neurovascular disease with a range of severity and symptoms, yet
mostly studied as one phenotype in genome-wide association studies (GWAS). Here we …

The epidemiology of vestibular migraine: a population-based survey study

EJ Formeister, HG Rizk, MA Kohn… - Otology & …, 2018 - journals.lww.com
Objectives: 1. Describe the epidemiology of vestibular migraine (VM) in the United States,
using data from the 2008 National Health Interview Survey (NHIS). 2. Characterize the …

Association of migraine with aura and other risk factors with incident cardiovascular disease in women

T Kurth, PM Rist, PM Ridker, G Kotler, V Bubes… - JAMA, 2020 - jamanetwork.com
Importance Migraine with aura is known to increase the risk of cardiovascular disease
(CVD). The absolute contribution of migraine with aura to CVD incidence in relation to other …

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework

Y Cho, PC Haycock, E Sanderson, TR Gaunt… - Nature …, 2020 - nature.com
In Mendelian randomization (MR) analysis, variants that exert horizontal pleiotropy are
typically treated as a nuisance. However, they could be valuable in identifying alternative …

Myocardial infarction, stroke and cardiovascular mortality among migraine patients: a systematic review and meta-analysis

CYH Ng, BYQ Tan, YN Teo, YH Teo, NLX Syn… - Journal of …, 2022 - Springer
Background An increasing number of studies have shown an association between migraine
and cardiovascular disease, in particular cardio-and cerebro-vascular events. Methods …

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools

S Bahrami, G Hindley, BS Winsvold, KS O'Connell… - Brain, 2022 - academic.oup.com
Migraine is three times more prevalent in people with bipolar disorder or depression. The
relationship between schizophrenia and migraine is less certain although glutamatergic and …

Migraine and cardiovascular disease: what cardiologists should know

DN Kalkman, EGM Couturier… - European Heart …, 2023 - academic.oup.com
Migraine is a chronic neurovascular disease with a complex, not fully understood
pathophysiology with multiple causes. People with migraine suffer from recurrent moderate …

Genetic risk score for coronary disease identifies predispositions to cardiovascular and noncardiovascular diseases

I Ntalla, S Kanoni, L Zeng, O Giannakopoulou… - Journal of the American …, 2019 - jacc.org
Background: The taxonomy of cardiovascular (CV) diseases is divided into a broad
spectrum of clinical entities. Many such diseases coincide in specific patient groups and …