Hyperhidrosis in sleep disorders–A narrative review of mechanisms and clinical significance
J Idiaquez, JC Casar, ES Arnardottir… - Journal of Sleep …, 2023 - Wiley Online Library
Hyperhidrosis is characterized by excessive sweating beyond thermoregulatory needs that
affects patients' quality of life. It results from an excessive stimulation of eccrine sweat glands …
affects patients' quality of life. It results from an excessive stimulation of eccrine sweat glands …
Evidence for TRPV4 channel induced skin vasodilatation through NOS, COX, and KCa channel mechanisms with no effect on sweat rate in humans
N Fujii, GP Kenny, T Amano, Y Honda, N Kondo… - European Journal of …, 2019 - Elsevier
Transient receptor potential vanilloid 4 (TRPV4) channels exist in the endothelial cells of
cutaneous blood vessels and the secretory cells of eccrine sweat glands. We assessed if …
cutaneous blood vessels and the secretory cells of eccrine sweat glands. We assessed if …
TRPV4 channel blockade does not modulate skin vasodilation and sweating during hyperthermia or cutaneous postocclusive reactive and thermal hyperemia
Transient receptor potential vanilloid 4 (TRPV4) channels exist on vascular endothelial cells
and eccrine sweat gland secretory cells in human skin. Here, we assessed whether TRPV4 …
and eccrine sweat gland secretory cells in human skin. Here, we assessed whether TRPV4 …
K+ channel mechanisms underlying cholinergic cutaneous vasodilation and sweating in young humans: roles of KCa, KATP, and KV channels?
N Fujii, JC Louie, BD McNeely… - American Journal …, 2016 - journals.physiology.org
Acetylcholine released from cholinergic nerves is involved in heat loss responses of
cutaneous vasodilation and sweating. K+ channels are thought to play a role in regulating …
cutaneous vasodilation and sweating. K+ channels are thought to play a role in regulating …
Galanin receptors modulate cutaneous vasodilation elicited by whole-body and local heating but not thermal sweating in young adults
N Fujii, R Rakwal, J Shibato, Y Tanabe… - European Journal of …, 2023 - Elsevier
Galanin receptor subtypes GAL 1, GAL 2, and GAL 3 are involved in several biological
functions. We hypothesized that 1) GAL 3 receptor activation contributes to sweating but …
functions. We hypothesized that 1) GAL 3 receptor activation contributes to sweating but …
Regional variation in the reliability of sweat rate measured via the ventilated capsule technique during passive heating
The ventilated capsule technique is widely used to measure time‐dependent changes in
sweating in humans. However, evaluations of its reliability (consistency) have been …
sweating in humans. However, evaluations of its reliability (consistency) have been …
TMEM16A blockers T16Ainh‐A01 and benzbromarone do not modulate the regulation of sweating and cutaneous vasodilatation in humans in vivo
New Findings What is the central question of this study? Do transmembrane member 16A
(TMEM16A) blockers modulate the activation of heat loss responses of sweating and …
(TMEM16A) blockers modulate the activation of heat loss responses of sweating and …
Pretreatment of microneedles enhances passive transdermal administration of pilocarpine and pilocarpine-induced sweat production in humans
The development of an effective transdermal drug delivery protocol to eccrine sweat glands
is important for the advancement of research on the human sweating response. We …
is important for the advancement of research on the human sweating response. We …
The roles of the Na+/K+‐ATPase, NKCC, and K+ channels in regulating local sweating and cutaneous blood flow during exercise in humans in vivo
Abstract Na+/K+‐ATP ase has been shown to regulate the sweating and cutaneous vascular
responses during exercise; however, similar studies have not been conducted to assess the …
responses during exercise; however, similar studies have not been conducted to assess the …
Exercise intensity-and body region-specific differences in sweating in middle-aged-to-older men with and without type 2 diabetes
Type 2 diabetes is associated with reduced whole-body sweating during exercise-heat
stress. However, it is unclear if this impairment is related to exercise intensity and whether it …
stress. However, it is unclear if this impairment is related to exercise intensity and whether it …