Phenolic compounds and flavonoids are potential substitutes for bioactive agents in
pharmaceutical and medicinal sections to promote human health and prevent and cure …

Sepsis is a severe inflammatory response to systemic infection and is a threatening cause of
death in intensive care units. In recent years, a number of studies have been conducted on …

Background/aims Sepsis is one of the major problems encountered in intensive care units,
causing organ damage and increasing mortality. Suberosin (SBR) is a type of coumarin with …

Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by memory loss
and cognitive decline. Among the suggested pathogenic mechanisms of AD, the cholinergic …

Coumarin, a plant secondary metabolite, has various pharmacological activities, including
antioxidant stress and anti-inflammatory effects. Umbelliferone, a common coumarin …

Objectives We investigated, the effects of aprepitant (APRE) on the lung tissues of rats with
an experimental polymicrobial sepsis model (CLP: cecal ligation and puncture) …

We investigated the effects of luteolin (LUT) treatment on acute lung injury caused by cecal
ligation and puncture (CLP) induced septic rats. We also investigated the relation between …

Alzheimer's disease (AD) presents a growing global health concern. In recent decades,
natural and synthetic chromenone have emerged as promising drug candidates due to their …

Pomegranate peel contains bioactive ingredients such as flavonoids, ellagitannins,
phenolics and proanthocyanidin compounds with high antioxidant activity. Pomegranate …

Sepsis is a syndrome that includes physiological, pathological, and biochemical
abnormalities resulting from the host immune response to infection. Despite the improved …