Role of circular RNA in brain tumor development
Central nervous system tumors are a leading cause of cancer-related death in children and
adults, with medulloblastoma (MB) and glioblastoma (GBM) being the most prevalent …
adults, with medulloblastoma (MB) and glioblastoma (GBM) being the most prevalent …
Wnt signaling in brain tumors: A challenging therapeutic target
Simple Summary Wnt signaling is one of the main evolutionarily conserved developmental
pathways needed to instruct embryo formation and maintenance of organ tissues. Decades …
pathways needed to instruct embryo formation and maintenance of organ tissues. Decades …
Automatic image segmentation and online survival prediction model of medulloblastoma based on machine learning
L Zhou, Q Ji, H Peng, F Chen, Y Zheng, Z Jiao… - European …, 2024 - Springer
Objectives To develop a dynamic nomogram containing radiomics signature and clinical
features for estimating the overall survival (OS) of patients with medulloblastoma (MB) and …
features for estimating the overall survival (OS) of patients with medulloblastoma (MB) and …
A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma
MJ Kling, V Kesherwani, NK Mishra… - Journal of Experimental …, 2022 - Springer
Background Medulloblastoma (MB) patients with MYC oncogene amplification or
overexpression exhibit extremely poor clinical outcomes and respond poorly to current …
overexpression exhibit extremely poor clinical outcomes and respond poorly to current …
Marinopyrrole derivative MP1 as a novel anti-cancer agent in group 3 MYC-amplified Medulloblastoma
DW Coulter, YS Chhonker, D Kumar… - Journal of Experimental …, 2024 - Springer
Background Medulloblastoma (MB) patients with MYC oncogene amplification or
overexpression exhibit extremely poor prognoses and therapy resistance. However, MYC …
overexpression exhibit extremely poor prognoses and therapy resistance. However, MYC …
Systematic transcriptomic analysis of childhood medulloblastoma identifies N6-methyladenosine-dependent lncRNA signatures associated with molecular subtype …
Medulloblastoma, the most common malignant pediatric brain tumor, is classified into four
main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and …
main molecular subgroups, but group 3 and group 4 tumors are difficult to subclassify and …
STAT3 Inhibition Attenuates MYC Expression by Modulating Co-Activator Recruitment and Suppresses Medulloblastoma Tumor Growth by Augmenting Cisplatin …
KA Rohrer, H Song, A Akbar, Y Chen, S Pramanik… - Cancers, 2023 - mdpi.com
Simple Summary Medulloblastoma (MB) is a malignant brain tumor of childhood that occurs
in the cerebellum and accounts for 20–25% of all pediatric central nervous system tumors …
in the cerebellum and accounts for 20–25% of all pediatric central nervous system tumors …
Mechanistic insights into medulloblastoma relapse
K Peterson, M Turos-Cabal, AD Salvador… - Pharmacology & …, 2024 - Elsevier
Pediatric brain tumors are the leading cause of cancer-related deaths in children, with
medulloblastoma (MB) being the most common type. A better understanding of these …
medulloblastoma (MB) being the most common type. A better understanding of these …
Overcoming Treatment Resistance in Medulloblastoma: Underlying Mechanisms and Potential Strategies
H Slika, A Shahani, R Wahi, J Miller, M Groves, B Tyler - Cancers, 2024 - mdpi.com
Simple Summary Medulloblastoma is the most common type of malignant brain tumor that
occurs in the pediatric population. It is associated with significant morbidity and mortality due …
occurs in the pediatric population. It is associated with significant morbidity and mortality due …
Analysis of Copy Number Variation of DNA Repair/Damage Response Genes in Tumor Tissues
T Izumi - Base Excision Repair Pathway: Methods and Protocols, 2023 - Springer
Cells experience increased genome instability through the course of disease development
including cancer initiation and progression. Point mutations, insertion/deletions …
including cancer initiation and progression. Point mutations, insertion/deletions …