Urothelial carcinoma of the bladder comprises two long-recognized disease entities with
distinct molecular features and clinical outcome. Low-grade non-muscle-invasive tumours …

Cellular metabolism influences life and death decisions. An emerging theme in cancer
biology is that metabolic regulation is intricately linked to cancer progression. In part, this is …

Despite an increase in survival for children with acute lymphoblastic leukemia (ALL), the
outcome after relapse is poor. To understand the genetic events that contribute to relapse …

Objective Patients with urothelial carcinoma (UC) undergo rigorous surveillance for
recurrence. Noninvasive urine tests are not currently recommended by guideline panels …

The prognosis and treatment of bladder cancer have improved little in the past 20 years.
Bladder cancer remains a debilitating and often fatal disease, and is among the most costly …

Mitogen-activated protein kinase (MAPK) is an important signaling pathway in living beings
in response to extracellular stimuli. There are 5 main subgroups manipulating by a set of …

Prostate cancer (CaP) is the most common adult male cancer in the developed world. The
paucity of biomarkers to predict prostate tumor biology makes it important to identify key …

Once urinary bladder cancer (UBC) develops into muscle-invasive bladder cancer, its
mortality rate increases dramatically. However, the molecular mechanisms of UBC invasion …

Onco-miR-182-5p has been reported to be over-expressed in bladder cancer (BC) tissues
however a detailed functional analysis of miR-182-5p has not been carried out in BC …

Experimental urinary bladder tumours have been proposed as a useful model for the study
of urinary bladder carcinogenesis, as well as for evaluating new therapeutic strategies …