Tranexamic acid (TXA) is an effective hemostatic agent used for the reduction of blood loss
and transfusion. However, the safety profile of TXA remains in question due to a potential …

Objective. Tranexamic acid (TXA) is increasingly used in orthopedic surgery to reduce blood
loss; however, there are concerns about the risk of venous thromboembolic (VTE) …

Background A growing body of published research on tranexamic acid (TXA) suggests that it
is effective in reducing blood loss and the risk for transfusion in total knee arthroplasty (TKA) …

Background Tranexamic acid (TXA) is effective in reducing blood loss in total joint
arthroplasty (TJA), but concerns still remain regarding the drug's safety. The purpose of this …

The use of tranexamic acid (TXA) as an antifibrinolytic agent was initially approved by the
Food and Drug Administration to reduce bleeding in hemophiliacs undergoing tooth …

Objective The optimal dose and efficacy of tranexamic acid (TXA) and epsilon‐aminocaproic
acid (EACA) in total knee arthroplasty (TKA) were under controversial, and we aimed to …

What is known and objective This study was performed to compare the efficacy and safety of
combined administration of intravenous (IV) and intra‐articular (IA) tranexamic acid (TXA) …

Abstract Background The Fragility Index (FI) is a method for evaluating the robustness of
statistically significant findings from randomized controlled trials (RCTs) beyond the P value …

Drainage after total hip or knee arthroplasty (THA, TKA) used to be systematic to prevent
complications and notably hematoma and infection. However, improvement in practices, the …

Abundant literature confirms that intravenous (IV) and intra-articular (IA) administration of
tranexamic acid (TXA) reduces blood loss in total knee arthroplasty (TKA). Oral formulations …