Human leukocyte antigen (HLA) genes are associated with more diseases than any other
region of the genome. Highly polymorphic HLA genes produce variable haplotypes that are …

The HLA class II region encodes the strongest genetic contribution to insulin-dependent
diabetes mellitus (IDDM); however, the complex HLA associations with IDDM are not yet …

OBJECTIVE—The Type 1 Diabetes Genetics Consortium has collected type 1 diabetic
families worldwide for genetic analysis. The major genetic determinants of type 1 diabetes …

We report here our analysis of HLA class II alleles in 180 Caucasian nuclear families with at
least two children with insulin-dependent diabetes mellitus (IDDM). DRB1, DQA1, DQB1 …

Background: Polymorphisms in the interleukin‐1 (IL‐1) gene cluster have been associated
with an increased risk of developing certain diseases. A specific composite genotype of IL …

Ketosis-prone diabetes is heterogeneous. Its causes could include novel β-cell functional
defects. To characterize such defects, 103 patients with diabetic ketoacidosis were …

The direct involvement of the human leukocyte antigen class II DR‐DQ genes in type 1
diabetes (T1D) is well established, and these genes display a complex hierarchy of risk …

Context: The discrepancies in terms of human leukocyte antigen (HLA)-DRB1-DQA1-DQB1
conferred risks between latent autoimmune diabetes in adults (LADA) and type 1 diabetes …

Aims To analyse the genome‐wide association study (GWAS) data of patients with type 1
diabetes mellitus (T1D) in order to develop a risk score for the genetic effects on T1D risk …

The genetic predisposition to type 1 diabetes among Filipinos was examined by PCR/SSOP
HLA class I and II typing of 90 patients and 94 general population controls. The HLA‐DRB1 …