Oleoylethanolamide: A fat ally in the fight against obesity
JD Brown, EK Azari, JE Ayala - Physiology & behavior, 2017 - Elsevier
Obesity is a pandemic, gateway disease that has thrived in modern, sedentary, high calorie-
eating societies. Left unchecked, obesity and obesity-related diseases will continue to …
eating societies. Left unchecked, obesity and obesity-related diseases will continue to …
Saikosaponin D attenuates metabolic associated fatty liver disease by coordinately tuning PPARα and INSIG/SREBP1c pathway
Y Gu, S Duan, M Ding, Q Zheng, G Fan, X Li, Y Li, C Liu… - Phytomedicine, 2022 - Elsevier
Background Metabolic associated fatty liver disease (MAFLD) is a progressive chronic liver
disease, yet there is still a lack of effective pharmacological therapies at present …
disease, yet there is still a lack of effective pharmacological therapies at present …
Cooperative role of the glucagon‐like peptide‐1 receptor and β3‐adrenergic‐mediated signalling on fat mass reduction through the downregulation of PKA/AKT …
Aim To explore the cooperation of GLP‐1 receptor and β3‐adrenergic receptor (β3‐AR)‐
mediated signalling in the control of fat mass/feeding behaviour by studying the effects of a …
mediated signalling in the control of fat mass/feeding behaviour by studying the effects of a …
Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat
β-adrenergic receptor activation promotes brown adipose tissue (BAT) β-oxidation and
thermogenesis by burning fatty acids during uncoupling respiration. Oleoylethanolamide …
thermogenesis by burning fatty acids during uncoupling respiration. Oleoylethanolamide …
Palmitoleoylethanolamide is an efficient anti-obesity endogenous compound: comparison with oleylethanolamide in diet-induced obesity
R Tovar, AL Gavito, A Vargas, L Soverchia… - Nutrients, 2021 - mdpi.com
Obesity is currently a major epidemic in the developed world. However, we lack a wide
range of effective pharmacological treatments and therapies against obesity, and those …
range of effective pharmacological treatments and therapies against obesity, and those …
Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-α agonist Wy-14643 in high-fat diet fed rats
E Karimian Azari, C Leitner, T Jaggi, W Langhans… - PloS one, 2013 - journals.plos.org
PPAR-α plays a key role in lipid metabolism; it enhances fatty acid oxidation (FAO) and
ketogenesis. Pharmacological PPAR-α activation improves insulin sensitivity and reduces …
ketogenesis. Pharmacological PPAR-α activation improves insulin sensitivity and reduces …
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and …
P Rivera, L Bindila, A Pastor, M Pérez-Martín… - Frontiers in cellular …, 2015 - frontiersin.org
Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis.
The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597 …
The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597 …
Di‐(2‐ethylhexyl) phthalate (DEHP) promoted hepatic lipid accumulation by activating Notch signaling pathway
Y Zhang, H Qian, J Wang, Y Zhu, X Miao… - Environmental …, 2023 - Wiley Online Library
Abstract Di‐(2‐ethylhexyl) phthalate (DEHP) and mono‐2‐ethylhexyl phthalate (MEHP) can
induce hepatic lipid metabolism disorders, while the molecular mechanism still remain …
induce hepatic lipid metabolism disorders, while the molecular mechanism still remain …
Exposure to a highly caloric palatable diet during the perinatal period affects the expression of the endogenous cannabinoid system in the brain, liver and adipose …
MT Ramírez-López, R Arco, J Decara, M Vázquez… - PLoS one, 2016 - journals.plos.org
Recent studies have linked gestational exposure to highly caloric diets with a disrupted
endogenous cannabinoid system (ECS). In the present study, we have extended these …
endogenous cannabinoid system (ECS). In the present study, we have extended these …