Twenty years of ModelDB and beyond: building essential modeling tools for the future of neuroscience

RA McDougal, TM Morse, T Carnevale… - Journal of computational …, 2017 - Springer
Neuron modeling may be said to have originated with the Hodgkin and Huxley action
potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over …

Modernizing the NEURON simulator for sustainability, portability, and performance

O Awile, P Kumbhar, N Cornu… - Frontiers in …, 2022 - frontiersin.org
The need for reproducible, credible, multiscale biological modeling has led to the
development of standardized simulation platforms, such as the widely-used NEURON …

[HTML][HTML] Open source brain: a collaborative resource for visualizing, analyzing, simulating, and developing standardized models of neurons and circuits

P Gleeson, M Cantarelli, B Marin, A Quintana… - Neuron, 2019 - cell.com
Computational models are powerful tools for exploring the properties of complex biological
systems. In neuroscience, data-driven models of neural circuits that span multiple scales are …

Hybrid scheme for modeling local field potentials from point-neuron networks

E Hagen, D Dahmen, ML Stavrinou, H Lindén… - Cerebral …, 2016 - academic.oup.com
With rapidly advancing multi-electrode recording technology, the local field potential (LFP)
has again become a popular measure of neuronal activity in both research and clinical …

Full-scale scaffold model of the human hippocampus CA1 area

D Gandolfi, J Mapelli, SMG Solinas… - Nature Computational …, 2023 - nature.com
The increasing availability of quantitative data on the human brain is opening new avenues
to study neural function and dysfunction, thus bringing us closer and closer to the …

Reproducibility in computational neuroscience models and simulations

RA McDougal, AS Bulanova… - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
Objective: Like all scientific research, computational neuroscience research must be
reproducible. Big data science, including simulation research, cannot depend exclusively on …

A realistic morpho-anatomical connection strategy for modelling full-scale point-neuron microcircuits

D Gandolfi, J Mapelli, S Solinas, R De Schepper… - Scientific Reports, 2022 - nature.com
The modeling of extended microcircuits is emerging as an effective tool to simulate the
neurophysiological correlates of brain activity and to investigate brain dysfunctions …

Competing mechanisms of gamma and beta oscillations in the olfactory bulb based on multimodal inhibition of mitral cells over a respiratory cycle

F David, E Courtiol, N Buonviso, N Fourcaud-Trocmé - Eneuro, 2015 - eneuro.org
Gamma (∼ 40-90 Hz) and beta (∼ 15-40 Hz) oscillations and their associated neuronal
assemblies are key features of neuronal sensory processing. However, the mechanisms …

Does the number of functional olfactory receptor genes predict olfactory sensitivity and discrimination performance in mammals?

Q Martinez, E Amson, M Laska - Journal of Evolutionary Biology, 2024 - academic.oup.com
The number of functional genes coding for olfactory receptors differs markedly between
species and has repeatedly been suggested to be predictive of a species' olfactory …

NeuroML-DB: Sharing and characterizing data-driven neuroscience models described in NeuroML

J Birgiolas, V Haynes, P Gleeson… - PLoS computational …, 2023 - journals.plos.org
As researchers develop computational models of neural systems with increasing
sophistication and scale, it is often the case that fully de novo model development is …