Colonic diverticular disease

A Tursi, C Scarpignato, LL Strate, A Lanas… - Nature Reviews …, 2020 - nature.com
Diverticula are outpouchings of the intestinal wall and are common anatomical alterations
detected in the human colon. Colonic diverticulosis (the presence of diverticula in the colon; …

Molecular regulation of vascular smooth muscle cell differentiation in development and disease

GK Owens, MS Kumar… - Physiological reviews, 2004 - journals.physiology.org
The focus of this review is to provide an overview of the current state of knowledge of
molecular mechanisms/processes that control differentiation of vascular smooth muscle cells …

the pathophysiology and medical management of diverticulosis and diverticular disease of the colon

A Tursi, A Papa, S Danese - Alimentary pharmacology & …, 2015 - Wiley Online Library
Background The incidence of diverticulosis and diverticular disease of the colon, including
diverticulitis, is increasing worldwide, and becoming a significant burden on national health …

Pathophysiology of diverticular disease: from diverticula formation to symptom generation

MR Barbaro, C Cremon, D Fuschi, G Marasco… - International Journal of …, 2022 - mdpi.com
Diverticular disease is a common clinical problem, particularly in industrialized countries. In
most cases, colonic diverticula remain asymptomatic throughout life and sometimes are …

Diverticulosis today: unfashionable and still under-researched

A Tursi - Therapeutic Advances in Gastroenterology, 2016 - journals.sagepub.com
Diverticulosis of the colon is a widespread disease, and its prevalence is increasing
especially in the developing world. The underlying pathological mechanisms that cause the …

Heritability and familial aggregation of diverticular disease: a population-based study of twins and siblings

LL Strate, R Erichsen, JA Baron, J Mortensen… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Little is known about the role of heritable factors in diverticular
disease. We evaluated the contribution of heritable factors to the development of diverticular …

The human enteric nervous system

M Schemann, M Neunlist - Neurogastroenterology & Motility, 2004 - Wiley Online Library
Decades of work in animal models have demonstrated that the enteric nervous system
(ENS) plays a key role in controlling gut functions. Recent advances made it possible to …

[HTML][HTML] Diet, ageing and genetic factors in the pathogenesis of diverticular disease

DM Commane, RP Arasaradnam, S Mills… - World journal of …, 2009 - ncbi.nlm.nih.gov
Diverticular disease (DD) is an age-related disorder of the large bowel which may affect half
of the population over the age of 65 in the UK. This high prevalence ranks it as one of the …

[HTML][HTML] Diverticular disease: a review on pathophysiology and recent evidence

N Piscopo, P Ellul - The Ulster medical journal, 2020 - ncbi.nlm.nih.gov
Diverticular disease is common condition globally, especially in Western countries.
Diverticulitis, Symptomatic uncomplicated Diverticular disease and Segmental Colitis …

Uncomplicated diverticular disease of the colon

L Petruzziello, F Iacopini, M Bulajic… - Alimentary …, 2006 - Wiley Online Library
Diverticular disease of the colon is the fifth most important gastrointestinal disease in terms
of direct and indirect healthcare costs in western countries. Uncomplicated diverticular …