General anesthesia has been unequivocally linked to abnormal development of the central nervous system, leading to neurocognitive impairments in laboratory models. In vitro and in …
Background: Children are required to fast before elective general anesthesia. This study hypothesized that prolonged fasting causes volume depletion that manifests as low blood …
Background: Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective …
F Weber, GP Scoones - Pediatric Anesthesia, 2019 - Wiley Online Library
Safeguarding cerebral function is of major importance during pediatric anesthesia. Premature, ex‐premature, and full‐term neonates can be vulnerable to physiological …
Objective Acute kidney injury is a severe complication and one of the stronger risk factors for death in patients undergoing cardiac surgery. The relationship between postoperative brain …
ME McCann, JK Lee, T Inder - Anesthesia & Analgesia, 2019 - journals.lww.com
Infants who undergo surgical procedures in the first few months of life are at a higher risk of death or subsequent neurodevelopmental abnormalities. Although the pathogenesis of …
Goal-directed therapy based on brain-oxygen saturation (bSo2) is controversial and hotly debated. While meta-analyses of aggregated data have shown no clinical benefit for brain …
L Li, J Zhang, J Li, Y Ren, Z Gao, J Gao, F Zhang… - BMC …, 2023 - Springer
Background It is believed that negative postoperative behavioral changes (NPOBC) is associated with negative perioperative outcomes in children. The importance of …
I Yuan, T Xu, CD Kurth - Anesthesiology clinics, 2020 - anesthesiology.theclinics.com
Inhaled sevoflurane and intravenous (IV) propofol are 2 of the primary drugs used to anesthetize children. Dosing for these agents is guided by monitoring expired concentration …