The merger of photoredox catalysis with transition metal catalysis, termed metallaphotoredox catalysis, has become a mainstay in synthetic methodology over the past …
J Beaudelot, S Oger, S Perusko, TA Phan… - Chemical …, 2022 - ACS Publications
Photocatalyzed and photosensitized chemical processes have seen growing interest recently and have become among the most active areas of chemical research, notably due …
Asymmetric catalysis is a major theme of research in contemporary synthetic organic chemistry. The discovery of general strategies for highly enantioselective photochemical …
L Candish, KD Collins, GC Cook, JJ Douglas… - Chemical …, 2021 - ACS Publications
In the pursuit of new pharmaceuticals and agrochemicals, chemists in the life science industry require access to mild and robust synthetic methodologies to systematically modify …
The replacement of benzene rings with sp 3-hybridized bioisosteres in drug candidates generally improves pharmacokinetic properties while retaining biological activity,,,–. Rigid …
The late stage functionalization (LSF) of complex biorelevant compounds is a powerful tool to speed up the identification of structure–activity relationships (SARs) and to optimize …
Alkyl radicals are key intermediates in organic synthesis. Their classic generation from alkyl halides has a severe drawback due to the employment of toxic tin hydrides to the point that …
The past decade has witnessed the emergence of N-(acyloxy) phthalimides (NHPI esters) and its derivatives at the forefront of synthetic methods facilitating the construction of diverse …
HA Sakai, DWC MacMillan - Journal of the American Chemical …, 2022 - ACS Publications
Alcohols and carboxylic acids are among the most commercially abundant, synthetically versatile, and operationally convenient functional groups in organic chemistry. Under visible …