Water is an essential participant in the stability, structure, dynamics, and function of proteins
and other biomolecules. Thermodynamically, changes in the aqueous environment affect …

We present an overview of protein dynamics based mostly on results of neutron scattering,
dielectric relaxation spectroscopy and molecular dynamics simulations. We identify several …

One of the fundamental challenges of physical biology is to understand the relationship
between protein dynamics and function. At physiological temperatures, functional motions …

Hydration water is the natural matrix of biological macromolecules and is essential for their
activity in cells. The coupling between water and protein dynamics has been intensively …

Understanding the role of water in biological processes remains a central challenge in the
life sciences. Water structures in hydration shells of biomolecules are difficult to study in situ …

Terahertz (THz) spectroscopy has turned out to be a powerful tool which is able to shed new
light on the role of water in biomolecular processes. The low frequency spectrum of the …

We present a detailed analysis of the picosecond-to-nanosecond motions of green
fluorescent protein (GFP) and its hydration water using neutron scattering spectroscopy and …

The dynamics of water molecules within the hydration shell surrounding a biomolecule can
have a crucial influence on its biochemical function. Characterizing their properties and the …

Neutron scattering studies provide important information in structural biology that is not
accessible using other approaches. The uniqueness of the technique, and its …

Understanding adaptation to extreme environments remains a challenge of high
biotechnological potential for fundamental molecular biology. The cytosol of many …