Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation

AM Sebastiao, JA Ribeiro - Brain Research, 2015 - Elsevier
Synaptic plasticity mechanisms, ie the sequence of events that underlies persistent changes
in synaptic strength as a consequence of transient alteration in neuronal firing, are greatly …

Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimer's disease via activation of adenosine A1 receptor

Y Kong, Q Peng, N Lv, J Yuan, Z Deng, X Liang… - Neuroscience …, 2020 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia, characterised by
advanced cognitive and memory deterioration with no effective treatments available …

CB1 Activity Drives the Selection of Navigational Strategies: A Behavioral and c-Fos Immunoreactivity Study

D Laricchiuta, F Balsamo, C Fabrizio… - International Journal of …, 2020 - mdpi.com
To promote efficient explorative behaviors, subjects adaptively select spatial navigational
strategies based on landmarks or a cognitive map. The hippocampus works alone or in …

Caffeine and adenosine receptor modulation of cannabinoid influence upon cognitive function

VC Sousa, JA Ribeiro, AM Sebastião - Journal of Caffeine Research, 2013 - liebertpub.com
A1 and CB1 receptors are main targets for the cognitive effects of caffeine and Δ9-
tetrahydrocannabinol (THC), two of the most heavily consumed psychoactive substances …

Aetiology of Addiction

OM Lesch, H Walter, C Wetschka… - Alcohol and Tobacco …, 2020 - Springer
This chapter pays attention to psychological, social and biological theories of addiction
development. Different factors, their relevance as well as their loading, which differ in clinical …

Efeitos bioquímicos e comportamentais do pré-tratamento com agonista inverso CB1 na sinalização inflamatória desencadeada por LPS em camundongos.

BSL Souza - 2017 - teses.usp.br
O sistema canabinóide endógeno tem uma importante função modulatória em muitos
processos neurobiológicos, incluindo a neuroproteção, a plasticidade neuronal e a …

Relationship Between the Adenosine A1 Receptor and cGMP Levels in the Hippocampus: Implications on Neurotransmission and Synaptic Plasticity

ASRP Serpa - 2015 - search.proquest.com
The cyclic nucleotides cAMP and cGMP are second messengers whose levels are
modulated by G proteins-coupled receptors, and regulate multiple brain functions, including …

Ätiologie der Abhängigkeitserkrankungen

OM Lesch, H Walter, M Hesselbrock… - Alkohol und Tabak …, 2020 - Springer
Bei allen Erkrankungen werden psychologische, soziale, biologische und genetische
Ursachen vermutet. Nur wenige dieser ätiologischen Überlegungen führen jedoch zu …