Leishmaniasis is a vector-borne zoonotic disease caused by protozoan parasites of the
genus Leishmania, which are responsible for numerous clinical manifestations, such as …

Introduction: Among the drugs in clinical use for the treatment of leishmaniases,
amphotericin B (AmB) is the most effective and has been the most extensively studied for the …

Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to
establish the highest remedial benefit from a novel anti-ischemic medicine ie NRG. Methods …

Our goal was to design nanocarriers that specifically target and deliver therapeutics to
polarized macrophages. Mannose receptors are highly overexpressed on polarized …

Drimenol, a phytochemical with a distinct odor is found in edible aromatic plants, such as
Polygonum minus (known as kesum in Malaysia) and Drimys winteri. Recently, drimenol has …

Polymers have long been employed as carriers of choice for efficient delivery of therapeutic
agents. Several block copolymers including triblock copolymers have been designed using …

This study aimed to evaluate the efficacy of glucantime and amphotericin B (AmB)
encapsulated in niosome against cutaneous leishmaniasis (CL) using in vitro and in vivo …

Leishmaniasis is a prevalent parasitic infection belonging to neglected tropical diseases. It is
caused by Leishmania protozoan parasites transmitted by sandflies and it is responsible for …

Leishmaniasis is a neglected infectious disease caused by protozoan parasites from
Leishmania genus species, affecting millions of people, in several countries. The current …

The current study was designed to enhance the brain bioavailability and to extract maximum
therapeutic benefit from a novel antidepressant drug, agomelatine. For this purpose, a …