Immunomodulatory effect of adipose-derived stem cells: the cutting edge of clinical application

S Ceccarelli, P Pontecorvi, E Anastasiadou… - Frontiers in cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) represent a promising tool for soft tissue engineering as
well as for clinical treatment of inflammatory and autoimmune pathologies. The well …

The potential of adipose stem cells in regenerative medicine

B Lindroos, R Suuronen, S Miettinen - Stem Cell Reviews and Reports, 2011 - Springer
Adipose stem cells (ASCs) are an attractive and abundant stem cell source with therapeutic
applicability in diverse fields for the repair and regeneration of acute and chronically …

A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential

Y Petrenko, I Vackova, K Kekulova, M Chudickova… - Scientific reports, 2020 - nature.com
Multipotent mesenchymal stromal cells (MSCs) can be considered an accessible therapeutic
tool for regenerative medicine. Here, we compared the growth kinetics, immunophenotypic …

Adipose-derived stem cells induce angiogenesis via microvesicle transport of miRNA-31

T Kang, TM Jones, C Naddell… - Stem cells …, 2016 - academic.oup.com
Cell secretion is an important mechanism for stem cell-based therapeutic angiogenesis,
along with cell differentiation to vascular endothelial cells or smooth muscle cells. Cell …

First experience in humans using adipose tissue–derived regenerative cells in the treatment of patients with ST-segment elevation myocardial infarction

JH Houtgraaf, WK den Dekker, BM van Dalen… - Journal of the American …, 2012 - jacc.org
To the Editor: In preclinical animal models of acute myocardial infarction (AMI),
administration of freshly isolated adipose tissue–derived regenerative cells (ADRCs) …

Transplantation of adipose tissue and stem cells: role in metabolism and disease

TT Tran, CR Kahn - Nature Reviews Endocrinology, 2010 - nature.com
Humans and other mammals have three main adipose tissue depots: visceral white adipose
tissue, subcutaneous white adipose tissue and brown adipose tissue, each of which …

Therapeutic angiogenesis of adipose-derived stem cells for ischemic diseases

L Zhao, T Johnson, D Liu - Stem cell research & therapy, 2017 - Springer
Ischemic diseases, the leading cause of disability and death, are caused by the stenosis or
obstruction of arterioles/capillaries that is not compensated for by vessel dilatation or …

Adipose derived stromal cell (ADSC) injections for pain management of osteoarthritis in the human knee joint

PB Fodor, SG Paulseth - Aesthetic surgery journal, 2016 - academic.oup.com
Background This safety and feasibility study used autologous adipose-derived stromal
vascular cells (the stromal vascular fraction [SVF] of adipose tissue), to treat 8 osteoarthritic …

Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb

D Zhu, TK Johnson, Y Wang, M Thomas… - Stem cell research & …, 2020 - Springer
Background M2 macrophages and exosomes from adipose-derived stem cells (ASCs) are
both reported to promote angiogenesis. However, the possible synergistic effects between …

Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies

N D'souza, F Rossignoli, G Golinelli, G Grisendi… - BMC medicine, 2015 - Springer
Regenerative medicine relying on cell and gene therapies is one of the most promising
approaches to repair tissues. Multipotent mesenchymal stem/stromal cells (MSC), a …