Bleeding after cardiac surgery is a common and serious complication leading to transfusion
of multiple blood products and resulting in increased morbidity and mortality. Despite the …

Since the initial description of the phenomenon by Jennings et al 50 years ago, our
understanding of the underlying mechanisms of reperfusion injury has grown significantly …

Objective To identify medical practices that offer no net benefits. Methods We reviewed all
original articles published in 10 years (2001-2010) in one high-impact journal. Articles were …

Background Antifibrinolytic agents are commonly used during cardiac surgery to minimize
bleeding and to reduce exposure to blood products. We sought to determine whether …

Acute kidney injury (AKI) is a common and devastating medical condition, but no widely
accepted definition exists. A recent classification system by the Acute Dialysis Quality …

In September 2010, the first International Scientific Tendinopathy Symposium (ISTS) was
held in Umeå, Sweden, to establish a forum for original scientific and clinical insights in this …

Antifibrinolytic drugs are widely used to reduce blood loss during surgery. One serious
adverse effect of these drugs is convulsive seizures; however, the mechanisms underlying …

Efforts to develop new antiviral chemotherapeutic approaches are focusing on compounds
that target either influenza virus replication itself or host factor (s) that are critical to influenza …

BACKGROUND: Our aim was to investigate postoperative complications and mortality after
administration of aprotinin compared to tranexamic acid in an unselected, consecutive …

Both acute kidney injury (AKI) and chronic kidney disease (CKD) are highly prevalent in liver
transplantation, affecting 25% to 50% and 30% to 90% of recipients, respectively. The risk of …