Hair analysis as a biomonitor for toxicology, disease and health status

IM Kempson, E Lombi - Chemical Society Reviews, 2011 - pubs.rsc.org
Hair analysis receives a large amount of academic and commercial interest for wide-ranging
applications. However, in many instances, especially for elemental or 'mineral'analysis, the …

From differentiating metabolites to biomarkers

A Koulman, GA Lane, SJ Harrison… - Analytical and bioanalytical …, 2009 - Springer
The current developments in metabolomics and metabolic profiling technologies have led to
the discovery of several new metabolic biomarkers. Finding metabolites present in …

Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry

N Li, W Liu, W Li, S Li, X Chen, K Bi, P He - Clinical biochemistry, 2010 - Elsevier
OBJECTIVES: The identification of Alzheimer's disease (AD) biomarkers may allow for a less
invasive and more accurate diagnosis as well as serve as a predictor of future disease …

Hydrophilic interaction chromatography of polar and ionizable compounds by UHPLC

L Nováková, L Havlíková, H Vlčková - TrAC Trends in Analytical Chemistry, 2014 - Elsevier
In recent years, the popularity of hydrophilic interaction chromatography (HILIC) in the
analysis of small polar and ionizable molecules increased substantially. A large number of …

Metabolic profiling reveals growth stage variability in diatom exudates

A Barofsky, C Vidoudez… - Limnology and …, 2009 - Wiley Online Library
We studied the patterns of waterborne metabolites released by diatom cultures during
different growth phases. A carefully optimized enrichment procedure for metabolites from …

Metabonomics study of atherosclerosis rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry

F Zhang, Z Jia, P Gao, H Kong, X Li, J Chen, Q Yang… - Talanta, 2009 - Elsevier
An ultra fast liquid chromatography coupled with IT-TOF mass spectrometry (UFLC/MS-IT-
TOF) metabonomic approach was employed to study the plasma and urine metabolic …

Ultra high performance liquid chromatography as a tool for the discovery and the analysis of biomarkers of diseases: a review

L Denoroy, L Zimmer, B Renaud, S Parrot - Journal of Chromatography B, 2013 - Elsevier
The development and use of UHPLC-based methods for the identification, validation and
analysis of biomarkers for diseases is reviewed. The currents trends in types of stationary …

Application of faecal metabonomics on an experimental model of tubulointerstitial fibrosis by ultra performance liquid chromatography/high-sensitivity mass …

YY Zhao, XL Cheng, F Wei, X Bai, RC Lin - Biomarkers, 2012 - Taylor & Francis
Chronic renal failure (CRF) is a major challenge for the public healthcare problem. A novel
UPLC Q-TOF/MS method with MSE data collection mode was developed as a very effective …

Hair metabolomics in animal studies and clinical settings

WJ Jang, JY Choi, B Park, JH Seo, YH Seo, S Lee… - Molecules, 2019 - mdpi.com
Metabolomics is a powerful tool used to understand comprehensive changes in the
metabolic response and to study the phenotype of an organism by instrumental analysis. It …

An ultrasonication-assisted extraction and derivatization protocol for GC/TOFMS-based metabolite profiling

Y Liu, T Chen, Y Qiu, Y Cheng, Y Cao, A Zhao… - Analytical and …, 2011 - Springer
Conventional chemical derivatization of metabolites in biological specimens is time-
consuming, which limits the throughput and efficiency of metabolite profiling using a gas …