The cerebral cortex forms a sheet of neurons organized into a network of interconnected
modules that is highly expanded in humans and presumably enables our most refined …

In the last decade, single pulse electrical stimulation (SPES) has been used as an
investigational tool in the field of epilepsy surgery. Direct cortical stimulation applied at a …

Electroencephalography (EEG) is the standard diagnosis method for a wide variety of
diseases such as epilepsy, sleep disorders, encephalopathies, and coma, among others …

Purpose Deep brain stimulation (DBS) of the thalamus is an emerging surgical option for
people with medically refractory epilepsy that is not suitable for resective surgery, or in …

Epilepsy presurgical investigation may include focal intracortical single-pulse electrical
stimulations with depth electrodes, which induce cortico-cortical evoked potentials at distant …

Adaptive brain function is characterized by dynamic interactions within and between
neuronal circuits, often occurring at the time scale of milliseconds. These complex …

In patients with pharmaco-resistant focal epilepsies investigated with intracranial
electroencephalography (iEEG), direct electrical stimulations of a cortical region induce …

The preservation of language function during brain surgery still poses a challenge. No
intraoperative methods have been established to monitor the language network reliably. We …

Background and Purpose—Physiological effects of stroke are best assessed over entire
brain networks rather than just focally at the site of structural damage. Resting-state …

Epilepsy is a network phenomenon characterized by atypical activity during seizure both at
the level of single neurons and neural populations. The etiology of epilepsy is not …