Reduction or complete loss of traits is a common occurrence throughout evolutionary history.
In spite of this, numerous questions remain about why and how trait loss has occurred. Cave …

Zebrafish exhibit robust regeneration following spinal cord injury, promoted by macrophages
that control post-injury inflammation. However, the mechanistic basis of how macrophages …

The use of zebrafish in functional genomics and disease modeling has become popular due
to the ease of targeted mutagenesis with genome editing nucleases, ie, zinc finger …

Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we
report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of …

Background Genome editing using CRISPR/Cas9 has become a powerful tool in zebrafish
to generate targeted gene knockouts models. However, its use for targeted knock-in remains …

The zebrafish is a valuable vertebrate model to study cardiovascular formation and function
due to the facile visualization and rapid development of the circulatory system in its …

Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in
mammals. In contrast, adult zebrafish achieve functional recovery after complete SC …

The zebrafish is a powerful model system for studying animal development, for modeling
genetic diseases, and for large-scale in vivo functional genetics. Because of its ease of use …

The term glia describes a heterogenous collection of distinct cell types that make up a large
proportion of our nervous system. Although once considered the glue of the nervous system …

Many genes are known to regulate retinal regeneration after widespread tissue damage.
Conversely, genes controlling regeneration after limited cell loss, as per degenerative …