Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …

Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

For the past two decades, cellular senescence has been recognized as a central component
of the tumor cell response to chemotherapy and radiation. Traditionally, this form of …

An increase in life expectancy in developed countries has led to a surge of chronic aging-
related diseases. In the last few decades, several studies have provided evidence of the …

The dysfunction of adipose tissue with aging and the accumulation of senescent cells has
been implicated in the pathophysiology of chronic diseases. Recently interventions capable …

Epigallocatechin gallate (EGCG) is the main bioactive component of catechins
predominantly present in various types of tea. EGCG is well known for a wide spectrum of …

It has been thought that caloric restriction favors longevity and healthy aging where
autophagy plays a vital role. However, autophagy decreases during aging and that can lead …

The significance of diversity, composition, and functional attributes of the gut microbiota in
shaping human health is well recognized. Studies have shown that gut microbiota is closely …

Cellular senescence is emerging as a major hallmark of aging, and its modulation presents
an effective anti-aging strategy. This study attempted to understand the progression of …

As a vital inducible sensor, cyclooxygenase-2 (COX-2) plays an important role in the
progress of hepatic fibrogenesis. Activation of hepatic stellate cells (HSCs) in the liver can …