Obesity: pathophysiology and intervention

Y Zhang, J Liu, J Yao, G Ji, L Qian, J Wang, G Zhang… - Nutrients, 2014 - mdpi.com
Obesity presents a major health hazard of the 21st century. It promotes co-morbid diseases
such as heart disease, type 2 diabetes, obstructive sleep apnea, certain types of cancer, and …

Behavioral features in Prader-Willi syndrome (PWS): consensus paper from the International PWS Clinical Trial Consortium

L Schwartz, A Caixàs, A Dimitropoulos… - Journal of …, 2021 - Springer
Prader-Willi syndrome (PWS) is a rare neurodevelopmental genetic disorder associated with
a characteristic behavioral phenotype that includes severe hyperphagia and a variety of …

Recommendations for the diagnosis and management of Prader-Willi syndrome

AP Goldstone, AJ Holland, BP Hauffa… - The Journal of …, 2008 - academic.oup.com
Objective: The objective of the study was to provide recommendations for the diagnosis and
management of Prader-Willi syndrome throughout the life span to guide clinical practice …

Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders

V Grinevich, MG Desarménien, B Chini… - Frontiers in …, 2015 - frontiersin.org
Oxytocin (OT), the main neuropeptide of sociality, is expressed in neurons exclusively
localized in the hypothalamus. During the last decade, a plethora of neuroendocrine …

Clinical management of behavioral characteristics of Prader–Willi syndrome

AY Ho, A Dimitropoulos - Neuropsychiatric disease and treatment, 2010 - Taylor & Francis
Prader–Willi syndrome (PWS) is a complex neurodevelopmental disorder caused by an
abnormality on the long arm of chromosome 15 (q11–q13) that results in a host of …

Autistic-like symptomatology in Prader-Willi syndrome: a review of recent findings

A Dimitropoulos, RT Schultz - Current Psychiatry Reports, 2007 - Springer
Prader-Willi syndrome (PWS) is caused by either the structural loss of material or the
absence of gene expression from the paternally inherited copy of chromosome 15 in the q11 …

Social responsiveness and competence in Prader-Willi syndrome: direct comparison to autism spectrum disorder

A Dimitropoulos, A Ho, B Feldman - Journal of autism and developmental …, 2013 - Springer
Abstract Prader-Willi syndrome (PWS), a neurodevelopmental disorder primarily
characterized by hyperphagia and food preoccupations, is caused by the absence of …

Associations between repetitive questioning, resistance to change, temper outbursts and anxiety in Prader–Willi and Fragile‐X syndromes

K Woodcock, C Oliver… - Journal of Intellectual …, 2009 - Wiley Online Library
Background The behavioural phenotypes of Prader–Willi (PWS) and Fragile‐X (FraX)
syndromes both comprise repetitive behaviours with differences between the profiles. In this …

Cognitive profile in a large french cohort of adults with Prader–Willi syndrome: differences between genotypes

P Copet, J Jauregi, V Laurier, V Ehlinger… - Journal of …, 2010 - Wiley Online Library
Abstract Background Prader–Willi syndrome (PWS) is a rare genetic disorder characterised
by developmental abnormalities leading to somatic and psychological symptoms. These …

The relationship between compulsive behaviour and academic achievement across the three genetic subtypes of Prader–Willi syndrome

J Zarcone, D Napolitano, C Peterson… - Journal of …, 2007 - Wiley Online Library
Abstract Background Prader–Willi syndrome (PWS) is a genetic syndrome associated with
several physical, cognitive and behavioural characteristics. For many individuals with this …