Targeting AMP-activated protein kinase in sepsis

T Yumoto, CM Coopersmith - Frontiers in Endocrinology, 2024 - frontiersin.org
Sepsis is a global health challenge marked by limited clinical options and high mortality
rates. AMP-activated protein kinase (AMPK) is a cellular energy sensor that mediates …

[HTML][HTML] Advances and Challenges in Antiviral Development for Respiratory Viruses

LA De Jesús-González, M León-Juárez… - Pathogens, 2024 - mdpi.com
The development of antivirals for respiratory viruses has advanced markedly in response to
the growing threat of pathogens such as Influenzavirus (IAV), respiratory syncytial virus …

Association between lipid profile and clinical outcomes in COVID-19 patients

LA Ochoa-Ramírez, AK De la Herrán Arita… - Scientific Reports, 2024 - nature.com
High-density lipoprotein cholesterol (HDL-c) removes cholesterol, an essential component
in lipid rafts, and this cholesterol removal can regulate protein attachment to lipid rafts …

Acute Kidney Injury in the Context of COVID-19: An Analysis in Hospitalized Mexican Patients

JC Borrego-Moreno, MJ Cárdenas-de Luna… - Infectious Disease …, 2024 - mdpi.com
During the COVID-19 pandemic, a considerable proportion of patients developed a severe
condition that included respiratory failure, shock, or multiple organ dysfunction. Acute Kidney …

[HTML][HTML] Metformin in Antiviral Therapy: Evidence and Perspectives

I Halabitska, P Petakh, O Lushchak, I Kamyshna… - …, 2024 - pmc.ncbi.nlm.nih.gov
Metformin, a widely used antidiabetic medication, has emerged as a promising broad-
spectrum antiviral agent due to its ability to modulate cellular pathways essential for viral …