Optical imaging of voltage and calcium in cardiac cells & tissues

TJ Herron, P Lee, J Jalife - Circulation research, 2012 - Am Heart Assoc
Cardiac optical mapping has proven to be a powerful technology for studying cardiovascular
function and disease. The development and scientific impact of this methodology are well …

In-cell nanoelectronics: opening the door to intracellular electrophysiology

D Xu, J Mo, X Xie, N Hu - Nano-Micro Letters, 2021 - Springer
Establishing a reliable electrophysiological recording platform is crucial for cardiology and
neuroscience research. Noninvasive and label-free planar multitransistors and …

[HTML][HTML] Rapid cellular phenotyping of human pluripotent stem cell-derived cardiomyocytes using a genetically encoded fluorescent voltage sensor

JS Leyton-Mange, RW Mills, VS Macri, MY Jang… - Stem cell reports, 2014 - cell.com
In addition to their promise in regenerative medicine, pluripotent stem cells have proved to
be faithful models of many human diseases. In particular, patient-specific stem cell-derived …

High-throughput drug profiling with voltage-and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes

S Bedut, C Seminatore-Nole… - American Journal …, 2016 - journals.physiology.org
Cardiomyocytes derived from human embryonic stem cells (hESCs) or induced pluripotent
stem cells (hiPSCs) are increasingly used for in vitro assays and represent an interesting …

Electrophysiological heterogeneity in large populations of rabbit ventricular cardiomyocytes

Q Lachaud, MHN Aziz, FL Burton… - Cardiovascular …, 2022 - academic.oup.com
Aims Cardiac electrophysiological heterogeneity includes:(i) regional differences in action
potential (AP) waveform,(ii) AP waveform differences in cells isolated from a single …

Synchronized intracellular and extracellular recording of action potentials by three-dimensional nanoroded electroporation

D Xu, J Fang, M Zhang, H Wang, T Zhang… - Biosensors and …, 2021 - Elsevier
Electrophysiological study is an essential and significant strategy to explore the biological
mechanism of electrogenic cells. Current advanced nanodevices can achieve the high …

Fibroblast growth factor homologous factors modulate cardiac calcium channels

JA Hennessey, EQ Wei, GS Pitt - Circulation research, 2013 - Am Heart Assoc
Rationale: Fibroblast growth factor (FGF) homologous factors (FHFs; FGF11–14) are
intracellular modulators of voltage-gated Na+ channels, but their cellular distribution in …

Caveolae in ventricular myocytes are required for stretch-dependent conduction slowing

ER Pfeiffer, AT Wright, AG Edwards, JC Stowe… - Journal of molecular and …, 2014 - Elsevier
Mechanical stretch of cardiac muscle modulates action potential propagation velocity,
causing potentially arrhythmogenic conduction slowing. The mechanisms by which stretch …

Sensitive Intracellular Recording of Action Potentials by Supramolecular Self‐Assembled Electrodes

X Xiao, D Xu, H Han, DC Wang, SN Lei… - Advanced Functional …, 2024 - Wiley Online Library
Developing accurate electrophysiological recording platforms is crucial for investigating
cellular electrical activities, understanding the mechanisms underlying cardiovascular …

Design and use of organic voltage sensitive dyes

LM Loew - Membrane Potential Imaging in the Nervous System …, 2015 - Springer
The chemistry and the physics of voltage sensitive dyes (VSDs) should be understood and
appreciated as a prerequisite for their optimal application to problems in neuroscience …