Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release

N Kamaly, B Yameen, J Wu, OC Farokhzad - Chemical reviews, 2016 - ACS Publications
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

[HTML][HTML] Micro/nano-bubble-assisted ultrasound to enhance the EPR effect and potential theranostic applications

L Duan, L Yang, J Jin, F Yang, D Liu, K Hu, Q Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Drug delivery for tumor theranostics involves the extensive use of the enhanced permeability
and retention (EPR) effect. Previously, various types of nanomedicines have been …

Controlled drug release from pharmaceutical nanocarriers

JH Lee, Y Yeo - Chemical engineering science, 2015 - Elsevier
Nanocarriers providing spatiotemporal control of drug release contribute to reducing toxicity
and improving therapeutic efficacy of a drug. On the other hand, nanocarriers face unique …

Mechanical force-triggered drug delivery

Y Zhang, J Yu, HN Bomba, Y Zhu, Z Gu - Chemical reviews, 2016 - ACS Publications
Advanced drug delivery systems (DDS) enhance treatment efficacy of different therapeutics
in a dosage, spatial, and/or temporal controlled manner. To date, numerous chemical-or …

Field responsive materials: photo-, electro-, magnetic-and ultrasound-sensitive polymers

T Manouras, M Vamvakaki - Polymer Chemistry, 2017 - pubs.rsc.org
Stimuli responsive materials have attracted a great deal of attention during the last few
decades and are expected to lead to great advances in the areas of nano-and bio …

State-of-the-art materials for ultrasound-triggered drug delivery

SR Sirsi, MA Borden - Advanced drug delivery reviews, 2014 - Elsevier
Ultrasound is a unique and exciting theranostic modality that can be used to track drug
carriers, trigger drug release and improve drug deposition with high spatial precision. In this …

Future perspectives and recent advances in stimuli-responsive materials

D Roy, JN Cambre, BS Sumerlin - Progress in Polymer Science, 2010 - Elsevier
Interest in stimuli-responsive polymers has persisted over many decades, and a great deal
of work has been dedicated to developing environmentally sensitive macromolecules that …

[HTML][HTML] Polymeric micelles in anticancer therapy: targeting, imaging and triggered release

C Oerlemans, W Bult, M Bos, G Storm… - Pharmaceutical …, 2010 - Springer
Micelles are colloidal particles with a size around 5–100 nm which are currently under
investigation as carriers for hydrophobic drugs in anticancer therapy. Currently, five micellar …

Ultrasound-responsive nanocarriers in cancer treatment: A review

NS Awad, V Paul, NM AlSawaftah… - ACS Pharmacology & …, 2021 - ACS Publications
The safe and effective delivery of anticancer agents to diseased tissues is one of the
significant challenges in cancer therapy. Conventional anticancer agents are generally …