[HTML][HTML] Epidemiology, genetics and epigenetics of congenital heart diseases in twins

R Balasubramanian, S Vuppalapati, C Avanthika… - Cureus, 2021 - ncbi.nlm.nih.gov
Congenital heart defects (CHDs) refer to abnormalities in the heart function that arise at the
fetal stages. It is the most common birth defect that affects 0.8% of all liveborn infants. There …

Research progress and potential application of microRNA and other non-coding RNAs in forensic medicine

B Song, J Qian, J Fu - International journal of legal medicine, 2024 - Springer
At present, epigenetic markers have been extensively studied in various fields and have a
high value in forensic medicine due to their unique mode of inheritance, which does not …

Characterization of micro-RNA in women with different ovarian reserve

M Abu-Halima, LS Becker, BM Ayesh, SL Baus… - Scientific Reports, 2021 - nature.com
Women undergoing infertility treatment are routinely subjected to one or more tests of
ovarian reserve. Therefore, an adequate assessment of the ovarian reserve is necessary for …

Discordant congenital heart defects in monochorionic twins: risk factors and proposed pathophysiology

H Imany-Shakibai, O Yin, MR Russell, M Sklansky… - PLoS …, 2021 - journals.plos.org
A six-fold increase in congenital heart defects (CHD) exists among monochorionic (MC)
twins compared to singleton or dichorionic twin pregnancies. Though MC twins share an …

Insights from circulating microRNAs in cardiovascular entities in turner syndrome patients

M Abu-Halima, FS Oberhoffer, MA El Rahman… - PLoS …, 2020 - journals.plos.org
Background Turner syndrome (TS) is a chromosomal disorder, in which a female is partially
or entirely missing one of the two X chromosomes, with a prevalence of 1: 2500 live female …

miR-1306 induces cell apoptosis by targeting BMPR1B gene in the ovine granulosa cells

A Abdurahman, W Aierken, F Zhang… - Frontiers in …, 2022 - frontiersin.org
Bone morphogenetic protein receptor type-1B (BMPR1B) is one of the major gene for sheep
prolificacy. However, few studies investigated its regulatory region. In this study, we reported …

The needle in the haystack—Searching for genetic and epigenetic differences in monozygotic twins discordant for tetralogy of fallot

M Grunert, S Appelt, P Grossfeld… - Journal of Cardiovascular …, 2020 - mdpi.com
Congenital heart defects (CHDs) are the most common birth defect in human with an
incidence of almost 1% of all live births. Most cases have a multifactorial origin with both …

MicroRNA-183-3p is a predictor of worsening heart failure in adult patients with transposition of the great arteries and a systemic right ventricle

M Abu-Halima, E Meese, H Abdul-Khaliq… - Frontiers in …, 2021 - frontiersin.org
Aim: MicroRNAs (miRNAs) have been shown to play an important role in the progression of
heart failure (HF). The aim of our study was to analyze miRNAs in the blood of patients with …

Modeling Cardiotoxicity in Pediatric Oncology Patients Using Patient-Specific iPSC-Derived Cardiomyocytes Reveals Downregulation of Cardioprotective microRNAs

I Reinal, I Ontoria-Oviedo, M Selva, M Casini… - Antioxidants, 2023 - mdpi.com
Anthracyclines are widely used in the treatment of many solid cancers, but their efficacy is
limited by cardiotoxicity. As the number of pediatric cancer survivors continues to rise, there …

Integrated microRNA and mRNA expression profiling identifies novel targets and networks associated with Ebstein's anomaly

M Abu-Halima, V Wagner, LS Becker, BM Ayesh… - Cells, 2021 - mdpi.com
Little is known about abundance level changes of circulating microRNAs (miRNAs) and
messenger RNAs (mRNA) in patients with Ebstein's anomaly (EA). Here, we performed an …