The molecular details involved in the folding, dynamics, organization, and interaction of
proteins with other molecules are often difficult to assess by experimental techniques …

This review summarizes current knowledge about the mechanisms of timely binding and
dissociation of two nucleoid proteins, IHF and Fis, which play fundamental roles in the …

The human estrogen receptor α (hER α) is involved in the regulation of growth,
development, and tissue homeostasis. Agonists that bind to the receptor's ligand-binding …

The accurate reading of genetic information during transcription is essential for the
expression of genes. Sequence binding specificity very often is attributed to short-range …

Linker histone H1 is an essential regulatory protein for many critical biological processes,
such as eukaryotic chromatin packaging and gene expression. Mis-regulation of H1s is …

Replication protein A (RPA) serves as a hub protein inside eukaryotic cells, where it
coordinates crucial DNA metabolic processes and activates the DNA-damage response …

Amyloid peptides are known to self-assemble into larger aggregates that are linked to the
pathogenesis of many neurodegenerative disorders. In contrast to primary nucleation, recent …

Genomic reorganization, such as rearrangements and inversions, influences how genetic
information is organized within the bacterial genomes. Inversions, in particular, facilitate …

We review recent advances in modeling structural ensembles of transcription factors from
nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR) …

This study provides critical insights into the role of surface-mediated secondary processes in
Alzheimer's disease, particularly regarding the aggregation of Abeta42 peptides. Employing …