Pharmacogenetics of biological agents used in inflammatory bowel disease: a systematic review
R Lauro, F Mannino, N Irrera, F Squadrito, D Altavilla… - Biomedicines, 2021 - mdpi.com
Inflammatory Bowel Disease (IBD) comprises a group of disorders, in particular Crohn's
disease (CD) and ulcerative colitis (UC), characterized by chronic inflammation affecting the …
disease (CD) and ulcerative colitis (UC), characterized by chronic inflammation affecting the …
Apoptosis and inflammatory genes variants in primary non-response to anti-TNF therapy in Crohn's disease patients
L Lykowska-Szuber, M Walczak… - European Journal of …, 2023 - journals.lww.com
Anti-TNF therapy has indeed revolutionized the treatment of Crohn's disease, leading to
higher rates of response and remission in patients. However, a significant proportion of 20 …
higher rates of response and remission in patients. However, a significant proportion of 20 …
Genetic variability of inflammation and oxidative stress genes affects onset, progression of the disease and survival of patients with amyotrophic lateral sclerosis
M Ravnik-Glavač, K Goričar, D Vogrinc, B Koritnik… - Genes, 2022 - mdpi.com
Inflammation and oxidative stress are recognized as important contributors to amyotrophic
lateral sclerosis (ALS) disease pathogenesis. Our aim was to evaluate the impact of selected …
lateral sclerosis (ALS) disease pathogenesis. Our aim was to evaluate the impact of selected …
Effect of anti-TNF therapy on mucosal apoptosis genes expression in Crohn's disease
L Lykowska-Szuber, M Walczak… - Frontiers in …, 2021 - frontiersin.org
Crohn's disease (CD) is a chronic immune-mediated disorder for which there is not a fully
effective treatment. Moreover, biological therapy with anti-tumor necrosis factor-α (anti-TNF …
effective treatment. Moreover, biological therapy with anti-tumor necrosis factor-α (anti-TNF …
The Disease Model of Addiction: The Impact of Genetic Variability in the Oxidative Stress and Inflammation Pathways on Alcohol Dependance and Comorbid …
EE Tsermpini, K Goričar, B Kores Plesničar… - Antioxidants, 2023 - mdpi.com
Oxidative stress and neuroinflammation are involved in the pathogenesis of alcohol
addiction. However, little is known regarding the effect of genetic, behavioral, psychological …
addiction. However, little is known regarding the effect of genetic, behavioral, psychological …
CARD8 and IL1B Polymorphisms Influence MRI Brain Patterns in Newborns with Hypoxic-Ischemic Encephalopathy Treated with Hypothermia
K Esih, K Goričar, Z Rener-Primec, V Dolžan… - Antioxidants, 2021 - mdpi.com
Inflammation and oxidative stress are recognized as important contributors of brain injury in
newborns due to a perinatal hypoxic-ischemic (HI) insult. Genetic variability in these …
newborns due to a perinatal hypoxic-ischemic (HI) insult. Genetic variability in these …
Pharmacogenetic analysis of canonical versus noncanonical pathway of NF-kB in Crohn's disease patients under anti-tumor necrosis factor-α treatment
EF Stavrou, F Chatzopoulou, C Antonatos… - Pharmacogenetics …, 2022 - journals.lww.com
Objectives This study explores the potential of gene polymorphisms in the canonical and
noncanonical NF-kB signaling pathway as a prediction biomarker of anti-tumor necrosis …
noncanonical NF-kB signaling pathway as a prediction biomarker of anti-tumor necrosis …
Pharmacogenomics: Generalities and Applications in the Pharmaceutical Sciences
F Corrales-Araya, LR Solís-Alfaro… - Asian Journal of …, 2025 - article.ths100.in
Although the main objective of drugs is to improve the person's health, not all people present
the same response since it can be exacerbated, adequate, or absent. This variability is …
the same response since it can be exacerbated, adequate, or absent. This variability is …