[HTML][HTML] Unusual structures and unknown roles of FeS clusters in metalloenzymes seen from a resonance Raman spectroscopic perspective
G Caserta, L Zuccarello, C Barbosa, CM Silveira… - Coordination Chemistry …, 2022 - Elsevier
The universe of known biological FeS clusters is constantly enlarging. Besides the
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
conventional, well described [2Fe–2S],[3Fe–4S] and cubane [4Fe–4S] clusters, novel …
The intriguing mitoNEET: functional and spectroscopic properties of a unique [2Fe-2S] cluster coordination geometry
Despite the number of cellular and pathological mitoNEET-related processes, very few
details are known about the mechanism of action of the protein. The recently discovered …
details are known about the mechanism of action of the protein. The recently discovered …
Exploiting molecular symmetry to quantitatively map the excited-state landscape of iron–sulfur clusters
Cuboidal [Fe4S4] clusters are ubiquitous cofactors in biological redox chemistry. In the
[Fe4S4] 1+ state, pairwise spin coupling gives rise to six arrangements of the Fe valences …
[Fe4S4] 1+ state, pairwise spin coupling gives rise to six arrangements of the Fe valences …
Paramagnetic NMR to study iron sulfur proteins: 13C detected experiments illuminate the vicinity of the metal center
The robustness of NMR coherence transfer in proximity of a paramagnetic center depends
on the relaxation properties of the nuclei involved. In the case of Iron-Sulfur Proteins …
on the relaxation properties of the nuclei involved. In the case of Iron-Sulfur Proteins …
Relaxation-based NMR assignment: Spotlights on ligand binding sites in human CISD3
CISD3 is a mitochondrial protein belonging to the NEET proteins family, bearing two [Fe 2 S
2] clusters coordinated by CDGSH domains. At variance with the other proteins of the NEET …
2] clusters coordinated by CDGSH domains. At variance with the other proteins of the NEET …
The ISC machinery assembles [2Fe–2S] clusters by formation and fusion of [1Fe–1S] precursors
Iron–sulfur clusters are essential metallocofactors synthesized by multiprotein machineries
via an unclear multistep process. Here we report a step-by-step dissection of the [2Fe–2S] …
via an unclear multistep process. Here we report a step-by-step dissection of the [2Fe–2S] …
Biochemical and cellular characterization of the CISD3 protein: Molecular bases of cluster release and destabilizing effects of nitric oxide
The NEET proteins, an important family of iron-sulfur (Fe-S) proteins, have generated a
strong interest due to their involvement in diverse diseases such as cancer, diabetes, and …
strong interest due to their involvement in diverse diseases such as cancer, diabetes, and …
Paramagnetic nuclear magnetic resonance: The Toolkit
Nuclear Magnetic Resonance (NMR) spectroscopy is the ideal tool to address the structure,
reactivity and dynamics of both inorganic and biological substances. The knowledge of …
reactivity and dynamics of both inorganic and biological substances. The knowledge of …
NMR of Paramagnetic Proteins: 13C Derived Paramagnetic Relaxation Enhancements Are an Additional Source of Structural Information in Solution
In paramagnetic metalloproteins, longitudinal relaxation rates of 13C′ and 13Cα nuclei can
be measured using 13C detected experiments and converted into electron spin-nuclear spin …
be measured using 13C detected experiments and converted into electron spin-nuclear spin …
Iron-sulfur protein odyssey: exploring their cluster functional versatility and challenging identification
C Vallières, O Benoit, O Guittet, ME Huang… - Metallomics, 2024 - academic.oup.com
Abstract Iron-sulfur (Fe-S) clusters are an essential and ubiquitous class of protein-bound
prosthetic centers that are involved in a broad range of biological processes (eg respiration …
prosthetic centers that are involved in a broad range of biological processes (eg respiration …