A review on the use of computational methods to characterize, design, and optimize tissue engineering scaffolds, with a potential in 3D printing fabrication

S Zhang, S Vijayavenkataraman… - Journal of Biomedical …, 2019 - Wiley Online Library
The design and fabrication of tissue engineering scaffolds is a highly complex process. In
order to provide a proper architecture for cells to grow, proliferate, and differentiate to form …

Scaffolds from biomaterials: advantages and limitations in bone and tissue engineering

FN Alaribe, SL Manoto, SCKM Motaung - Biologia, 2016 - degruyter.com
Nowadays, there has been immense progress in developing materials to support
transplanted cells. Nevertheless, the complexity of tissues is far beyond what is found in the …

Compression behavior of lattice structures produced by selective laser melting: X-ray tomography based experimental and finite element approaches

Y Amani, S Dancette, P Delroisse, A Simar, E Maire - Acta Materialia, 2018 - Elsevier
The compression behavior of hollow architectured structures obtained by additive
manufacturing was investigated in this work. Two face-centered cubic structures with the …

The correlation of pore morphology, interconnectivity and physical properties of 3D ceramic scaffolds with bone ingrowth

AC Jones, CH Arns, DW Hutmacher, BK Milthorpe… - Biomaterials, 2009 - Elsevier
In the design of tissue engineering scaffolds, design parameters including pore size, shape
and interconnectivity, mechanical properties and transport properties should be optimized to …

[HTML][HTML] Finite element method (FEM), mechanobiology and biomimetic scaffolds in bone tissue engineering

A Boccaccio, A Ballini, C Pappalettere… - … journal of biological …, 2011 - ncbi.nlm.nih.gov
Techniques of bone reconstructive surgery are largely based on conventional, non-cell-
based therapies that rely on the use of durable materials from outside the patient's body. In …

Extrusion based rapid prototyping technique: an advanced platform for tissue engineering scaffold fabrication

ME Hoque, YL Chuan, I Pashby - Biopolymers, 2012 - Wiley Online Library
Advances in scaffold design and fabrication technology have brought the tissue engineering
field stepping into a new era. Conventional techniques used to develop scaffolds inherit …

Nondestructive micro-computed tomography for biological imaging and quantification of scaffold–bone interaction in vivo

GH van Lenthe, H Hagenmüller, M Bohner, SJ Hollister… - Biomaterials, 2007 - Elsevier
Scaffolds, also called bioscaffolds, are needed in all tissue engineering applications as
carriers for cells and biochemical factors, as constructs providing appropriate mechanical …

A finite element study of mechanical stimuli in scaffolds for bone tissue engineering

C Sandino, JA Planell, D Lacroix - Journal of biomechanics, 2008 - Elsevier
Mechanical stimuli are one of the factors that affect cell proliferation and differentiation in the
process of bone tissue regeneration. Knowledge on the specific deformation sensed by cells …

Modeling the biomechanics of the lamina cribrosa microstructure in the human eye

A Karimi, SM Rahmati, RG Grytz, CA Girkin, JC Downs - Acta biomaterialia, 2021 - Elsevier
Glaucoma is among the leading causes of blindness worldwide that is characterized by
irreversible damage to the retinal ganglion cell axons in the lamina cribrosa (LC) region of …

Finite element evaluations of the mechanical properties of polycaprolactone/hydroxyapatite scaffolds by direct ink writing: Effects of pore geometry

B Zhang, L Guo, H Chen, Y Ventikos… - Journal of the …, 2020 - Elsevier
Osteochondral (OC) defects usually involve the damage of both the cartilage and its
underneath subchondral bone. In recent years, tissue engineering (TE) has become the …