Candidate biomarkers in psychiatric disorders: state of the field
The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can
aid in objectively diagnosing patients and providing individualized treatment …
aid in objectively diagnosing patients and providing individualized treatment …
Neuroimaging biomarkers in schizophrenia
NV Kraguljac, WM McDonald… - American Journal of …, 2021 - Am Psychiatric Assoc
Schizophrenia is a complex neuropsychiatric syndrome with a heterogeneous genetic,
neurobiological, and phenotypic profile. Currently, no objective biological measures—that is …
neurobiological, and phenotypic profile. Currently, no objective biological measures—that is …
[HTML][HTML] Brain structure, function, and neurochemistry in schizophrenia and bipolar disorder—a systematic review of the magnetic resonance neuroimaging literature
Abstract Since Emil Kraepelin's conceptualization of endogenous psychoses as dementia
praecox and manic depression, the separation between primary psychotic disorders and …
praecox and manic depression, the separation between primary psychotic disorders and …
Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness
Neuroimaging studies of psychotic disorders have demonstrated abnormalities in structural
and functional connectivity involving widespread brain networks. However, these group …
and functional connectivity involving widespread brain networks. However, these group …
Functional connectivity in antipsychotic-treated and antipsychotic-naive patients with first-episode psychosis and low risk of self-harm or aggression: a secondary …
S Chopra, SM Francey, B O'Donoghue… - JAMA …, 2021 - jamanetwork.com
Importance Altered functional connectivity (FC) is a common finding in resting-state
functional magnetic resonance imaging (rs-fMRI) studies of people with psychosis, yet how …
functional magnetic resonance imaging (rs-fMRI) studies of people with psychosis, yet how …
Resting-state functional connectivity predictors of treatment response in schizophrenia–A systematic review and meta-analysis
We aimed to systematically synthesize and quantify the utility of pre-treatment resting-state
functional magnetic resonance imaging (rs-fMRI) in predicting antipsychotic response in …
functional magnetic resonance imaging (rs-fMRI) in predicting antipsychotic response in …
[HTML][HTML] Change in brain network topology as a function of treatment response in schizophrenia: a longitudinal resting-state fMRI study using graph theory
A number of neuroimaging studies have provided evidence in support of the hypothesis that
faulty interactions between spatially disparate brain regions underlie the pathophysiology of …
faulty interactions between spatially disparate brain regions underlie the pathophysiology of …
Ketamine modulates hippocampal neurochemistry and functional connectivity: a combined magnetic resonance spectroscopy and resting-state fMRI study in healthy …
A growing body of evidence suggests glutamate excess in schizophrenia and that N-methyl-
d-aspartate receptor (NMDAR) hypofunction on γ-aminobutyric acid (GABA) interneurons …
d-aspartate receptor (NMDAR) hypofunction on γ-aminobutyric acid (GABA) interneurons …
Hippocampal subregion abnormalities in schizophrenia: A systematic review of structural and physiological imaging studies
S Nakahara, M Matsumoto… - …, 2018 - Wiley Online Library
Aim The hippocampus is considered a key region in schizophrenia pathophysiology, but the
nature of hippocampal subregion abnormalities and how they contribute to disease …
nature of hippocampal subregion abnormalities and how they contribute to disease …
A functional connectome-based neural signature for individualized prediction of antipsychotic response in first-episode psychosis
Objective: Identification of robust biomarkers that predict individualized response to
antipsychotic treatment at the early stage of psychotic disorders remains a challenge in …
antipsychotic treatment at the early stage of psychotic disorders remains a challenge in …