Neuroblastoma, the most common childhood solid tumor, originates from primitive sympathetic nervous system cells. Epoxyazadiradione (EAD) is a limonoid derived from …
The anti-oxidant and anti-inflammatory effect of beta-glucogallin (BGG), a plant-derived natural product, was evaluated in both in vitro and in vivo studies. For the in vitro study, the …
SH Zhou, WH Liao, Y Yang, W Li, Y Wu, TT Wu… - ACS …, 2023 - ACS Publications
A series of (8-hydroxyquinoline) gallium (III) complexes (CP-1–4) was synthesized and characterized by single X-ray crystallography and density functional theory (DFT) …
A Singh, V Kumar, U Langeh, L Kapil, S Kaur… - Journal of Molecular …, 2024 - Springer
Today, we critically need alternative therapeutic options for chemotherapy-induced cognitive impairment (CICI), often known as chemo brain. Mitochondrial dysfunction and oxidative …
S Gupta, M Saha, R Singh, SB Ahmed… - Journal of Biomolecular …, 2024 - Taylor & Francis
Abstract The type II-C-KIT signaling network has been extensively studied for its potential as a target for cancer treatment, leading to the investigation of quinoline derivatives as …
S Rahimi, F Shirin, M Moassesfar, H Zafari… - Frontiers in Bioscience …, 2024 - imrpress.com
As one of the most common solid pediatric cancers, Neuroblastoma (NBL) accounts for 15% of all of the cancer-related mortalities in infants with increasing incidence all around the …
G Vergoten, C Bailly - Journal of Biochemical and Molecular …, 2022 - Wiley Online Library
Glycogen synthase kinase‐3β (GSK‐3β) is a target enzyme considered for the treatment of multiple human diseases, from neurodegenerative pathologies to viral infections and …
Diabetes is one of the fastest-growing metabolic disorders, nearly doubling the number of patients each year. There are different treatment approaches available for the management …
The inhibition of enzyme DPP-4 is pivotal for targeting type 2 diabetes mellitus (DM). The study introduces two series of novel 1, 3-dimethyl-3, 7-dihydro-1H-purine-2, 6-diones …