The emerging role of miR-20b in human cancer and other disorders: Pathophysiology and therapeutic implications

S Khalilian, H Abedinlou, BM Hussen… - Frontiers in …, 2022 - frontiersin.org
miR-20b is a microRNA with diverse and somehow contradictory roles in the pathogenesis
of human disorders, especially cancers. It has been known to be a tumor suppressor in …

[HTML][HTML] Tumor budding as a potential prognostic marker in determining the behavior of primary liver cancers

B Unal, MY Celik, EO Gedik, CI Bassorgun… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular (HCC) and intrahepatic cholangiocarcinoma (ICC), the most common
primary tumors of the liver, are among the most important causes of cancer deaths …

Identification and integrate analysis of key biomarkers for diagnosis and prognosis of non-small cell lung cancer based on bioinformatics analysis

K Gong, H Zhou, H Liu, T Xie, Y Luo… - … in cancer research …, 2021 - journals.sagepub.com
Background: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer
affecting humans. However, appropriate biomarkers for diagnosis and prognosis have not …

Identification and validation of potential miRNAs, as biomarkers for sepsis and associated lung injury: a network-based approach

S Ahmad, MM Ahmed, PMZ Hasan, A Sharma… - Genes, 2020 - mdpi.com
Sepsis is a dysregulated immune response disease affecting millions worldwide. Delayed
diagnosis, poor prognosis, and disease heterogeneity make its treatment ineffective …

Overexpression of hsa_circ_0008274 inhibited the progression of lung adenocarcinoma by regulating HMGA2 via sponging miR‐578

M Wang, M Ma, Y Yang, C Li, Y Wang, X Sun… - Thoracic …, 2021 - Wiley Online Library
Abstract Background Circular RNAs (circRNAs) had been identified as a non‐coding RNA
associated with many types of cancer in recent years. However, the involvement of …

A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2

S Zhou, C Zhang, Z Zhang, Y Hu, L Zhao… - Genes …, 2024 - Wiley Online Library
High‐mobility group AT‐hook 2 (HMGA2) is rearranged in various types of mesenchymal
tumors, particularly lipomas. HMGA2 is also co‐amplified with mouse double minute 2 …

Novel genome-wide DNA methylation profiling reveals distinct epigenetic landscape, prognostic model and cellular composition of early-stage lung adenocarcinoma

J Gan, M Huang, W Wang, G Fu, M Hu, H Zhong… - Journal of Translational …, 2024 - Springer
Background Lung adenocarcinoma (LUAD) has been a leading cause of cancer-related
mortality worldwide. Early intervention can significantly improve prognosis. DNA methylation …

Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways

Y Li, Y Leng, Y Dong, Y Song, Q Wu… - Oncology …, 2022 - spandidos-publications.com
Although great progress has been made in the early diagnosis and targeted therapy of lung
adenocarcinoma (LUAD), the survival of patients with LUAD remains unsatisfactory. There is …

GPC3 affects the prognosis of lung adenocarcinoma and lung squamous cell carcinoma

J Ning, S Jiang, X Li, Y Wang, X Deng, Z Zhang… - BMC pulmonary …, 2021 - Springer
Abstract Background Glypican 3 (GPC3) is a heparin sulphate proteoglycan whose
expression is associated with several malignancies. However, its expression in non-small …

Identification and validation of cyclin A2 and cyclin E2 as potential biomarkers in small cell lung cancer

X Zhang, L Yang, B Huang, J Yin, Y Wei - Oncology Research and …, 2023 - karger.com
Introduction: Small cell lung cancer (SCLC) is a special type of lung cancer sensitive to
radiotherapy and chemotherapy but is prone to drug resistance and recurrence and has a …