Objective To evaluate the quality of clinical practice guidelines (CPGs) for interventions in
management of osteoarthritis (OA) and to provide a synthesis of high‐quality CPG …

Objective To report the levels and trends of prevalence, deaths, and disability‐adjusted life
years (DALYs) due to musculoskeletal disorders, categorized as low back pain, neck pain …

Objectives Worldwide the use of opioids, both doctor-prescribed and illicit, has increased. In
most countries, opioids are first prescribed by general practitioners (GPs). Identifying factors …

Opioids are a group of analgesic agents commonly used in clinical practice. The three
classical opioid receptors are MOP, DOP and KOP. The NOP (N/OFQ) receptor is …

This Perspective adapts the ViolEx Model, a framework validated in several clinical
conditions, to better understand the role of expectations in the recovery and/or maintenance …

Background and purpose Chronic pain is a common comorbidity in those with functional
neurological disorder (FND); however, the prevalence and characteristics of FND in those …

Tramadol and tapentadol are fully synthetic and extensively used analgesic opioids,
presenting enhanced therapeutic and safety profiles as compared with their peers. However …

Purpose To investigate wellbeing and work impacts in younger people with persistent
shoulder pain. Materials and methods People aged 20–55 years with shoulder pain of> 6 …

An endemic increase in the number of deaths attributable to prescribed opioids is found in
all developed countries. In 2016 in the USA, more than 46 people died each day from …

Objective There are several treatment options for patients suffering from lumbar spinal
stenosis, including surgical and conservative care. Interspinous spacer decompression …