Cutaneous leishmaniasis: immune responses in protection and pathogenesis

P Scott, FO Novais - Nature Reviews Immunology, 2016 - nature.com
Cutaneous leishmaniasis is a major public health problem and causes a range of diseases
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …

Neutrophil-derived cytokines: facts beyond expression

C Tecchio, A Micheletti, MA Cassatella - Frontiers in immunology, 2014 - frontiersin.org
Polymorphonuclear neutrophils, besides their involvement in primary defense against
infections–mainly through phagocytosis, generation of toxic molecules, release of enzymes …

The multifaceted functions of neutrophils

TN Mayadas, X Cullere… - Annual Review of …, 2014 - annualreviews.org
Neutrophils and neutrophil-like cells are the major pathogen-fighting immune cells in
organisms ranging from slime molds to mammals. Central to their function is their ability to …

Diverse novel functions of neutrophils in immunity, inflammation, and beyond

A Mócsai - Journal of Experimental Medicine, 2013 - rupress.org
Neutrophils have long been considered simple suicide killers at the bottom of the hierarchy
of the immune response. That view began to change 10–20 yr ago, when the sophisticated …

Neutrophil function: from mechanisms to disease

B Amulic, C Cazalet, GL Hayes… - Annual review of …, 2012 - annualreviews.org
Neutrophils are the most abundant white blood cells in circulation, and patients with
congenital neutrophil deficiencies suffer from severe infections that are often fatal …

Leishmaniasis: complexity at the host–pathogen interface

P Kaye, P Scott - Nature reviews microbiology, 2011 - nature.com
Leishmania is a genus of protozoan parasites that are transmitted by the bite of
phlebotomine sandflies and give rise to a range of diseases (collectively known as …

Biological roles of neutrophil-derived granule proteins and cytokines

MA Cassatella, NK Östberg, N Tamassia… - Trends in …, 2019 - cell.com
Neutrophils, the most abundant white blood cells in human circulation, entertain intense
interactions with other leukocyte subsets, platelets, and stromal cells. Molecularly, such …

[HTML][HTML] Neutrophils in respiratory viral infections

C Johansson, FCM Kirsebom - Mucosal immunology, 2021 - Elsevier
Viral respiratory infections are a common cause of severe disease, especially in infants,
people who are immunocompromised, and in the elderly. Neutrophils, an important innate …

Neutrophil-derived chemokines on the road to immunity

C Tecchio, MA Cassatella - Seminars in immunology, 2016 - Elsevier
During recent years, it has become clear that polymorphonuclear neutrophils are remarkably
versatile cells, whose functions go far beyond phagocytosis and killing. In fact, besides …

Pro-and anti-inflammatory cytokines in cutaneous leishmaniasis: a review

N Maspi, A Abdoli, F Ghaffarifar - Pathogens and global health, 2016 - Taylor & Francis
Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro-
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …