Mitochondrial dysfunction is central to numerous diseases of oxidative stress. Changes in
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …

Following the acquisition of chloroplasts and mitochondria by eukaryotic cells during
endosymbiotic evolution, most of the genes in these organelles were either lost or …

MicroRNAs are well known to mediate translational repression and mRNA degradation in
the cytoplasm. Various microRNAs have also been detected in membrane …

Eukaryotic cells are characterized by their content of intracellular membrane-bound
organelles, including mitochondria as well as nuclei. These two DNA-containing …

Heteroplasmic mutations of mitochondrial DNA (mtDNA) are an important source of human
diseases. The mechanisms governing transmission, segregation and complementation of …

This is a completely revised edition of a comprehensive and popular introduction to the fast
moving area of Forensic Genetics. The text begins with key concepts needed to fully …

Neuronal mitochondria regulate synaptic physiology and cellular survival, and disruption of
their function or transport causes neurological disease. We present a fluorescence method …

▪ Abstract Mitochondrial DNA (mtDNA) exists in a nested hierarchy of populations. There are
multiple mtDNAs within each mitochondrion, a population of mitochondria in each cell …

A fundamental objective in molecular biology is to understand how DNA is organized in
concert with various proteins, RNA, and biological membranes. Mitochondria maintain and …

Mitochondria are central to retinal cell function and survival. There is increasing evidence to
support an association between mitochondrial dysfunction and a number of retinal …